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Multicentric intravascular lymphoma in the nervous system of a dog (case report)
Multicentric lymphomas belong to the most common diagnosed neoplasias in the dog and tend to respond very well to chemotherapy. This is a very unusual case: First, the lymphoma was intravascular, affecting central and peripheral nervous system and leading to neurological signs. Second, it progressed despite chemotherapy was performed. A very interesting case!

A 5-year-old, castrated male mixed-breed dog was presented for paraparesis, ataxia, hyperesthesia, and thrombocytopenia of 5 monthsÂ’ duration and recurrent seizures during the preceding 2 weeks.

Multifocal neurological, ophthalmological, pulmonary, and cardiac diseases were identified.

Magnetic resonance imaging and cerebrospinal fluid analysis supported a tentative diagnosis of neoplastic or inflammatory disease.

A computed tomography-guided biopsy provided both cytopathological and histopathological evidence of intravascular lymphoma.

The disease progressed despite chemotherapy with prednisone, L-asparginase, and vincristine.

Postmortem histopathological examinations suggested intravascular lymphoma in the central and peripheral nervous systems as well as in multiple other organ systems.

This is the first description of an antemortem diagnosis and treatment of intravascular lymphoma involving the central nervous system of a dog.





Source: William W. Bush, Juliene L. Throop, Patricia M. McManus, Amy S. Kapatkin, Charles H. Vite, Tom J. Van Winkle (2003): Intravascular Lymphoma Involving the Central and Peripheral Nervous Systems in a Dog. In: Journal of the American Animal Hospital Association 39:90-96 (2003)



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SMALL ANIMAL PRACTICE

Computed tomographic findings in dogs infected with Crenosoma vulpis
Crenosoma vulpis is a nematode lungworm found in wild and domestic canids in some parts of North America and Europe. Reported radiographic findings are nonspecific and consist of a combination of bronchial and interstitial changes of variable severity. This retrospective, case series study aimed to describe thoracic computed tomographic (CT) findings for a group of dogs with confirmed crenosomosis. Selection criteria were presentation with a chronic cough during the period of January 2016 to February 2017, evaluation by thoracic CT, and final diagnosis of C. vulpis infection based on bronchoscopic findings, bronchoalveolar lavage fluid analysis, and quantitative polymerase chain reaction.

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