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Collie eye anomaly in a non-Collie breed
Collie eye anomaly is a well-described problem in collies but not known in other breeds. This very interesting case report describes a dog with tetraparesis which was not a collie and showed a bilateral optic nerve coloboma and severe choroidal hypoplasia and also a lymphoma within the spinal cord. Is there a relationship between these two findings?

A 5-year-old, mixed-breed dog was presented for tetraparesis. Neurologic alterations included a decreased menace response in both eyes.

Therefore, an ophthalmic examination was requested.

The dog was visual, but menace response, dazzle and pupillary light reflexes were reduced bilaterally.

Indirect ophthalmoscopy revealed bilateral optic nerve coloboma and severe choroidal hypoplasia. These lesions closely resembled the ophthalmoscopic features of Collie eye anomaly (CEA).

In spite of treatment, the dog`s condition worsened and the animal was therefore euthanized. Histology of the globes confirmed severe choroidal hypoplasia and optic disc coloboma in both eyes.

The dog was diagnosed to have a lymphoma involving the spinal cord. The two entities were considered not related. As only moderate sight impairment was caused by the posterior segment anomalies, it is by chance that these lesions resembling CEA were found in this mixed-breed dog.



Source: Rampazzo, Antonella, D`Angelo, Antonio, Capucchio, Maria Teresa, Sereno, Sandra & Peruccio, Claudio (2005): Collie eye anomaly in a mixed-breed dog. In: Veterinary Ophthalmology 8 (5), 357-360.





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