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Vaccination against Flavobacterium psychrophilum in rainbow trout
Injection vaccines are not commonly used in fish. Is the recently tested injection vaccine against Flavobacterium psychrophilum in rainbow trout really an effective alternativecompared with the `classic` vaccine? It is, as this very interesting study shows.

Efficacy of mineral oil-based experimental injection vaccines against Flavobacterium psychrophilum were tested in rainbow trout, Oncorhynchus mykiss (Walbaum), under laboratory and field conditions.

The vaccines consisted of formalin- or heat-inactivated whole bacterium cell preparations of two different serotypes (Fd and Th) or a combination of serologically different F. psychrophilum (Fd and/or Th and/or FpT;Th).

Specific antibody responses against the bacterium in plasma and skin mucus were evaluated post-vaccination with enzyme-linked immunosorbent assay.

Efficacy of the vaccinations was determined by challenge trials to F. psychrophilum with the vaccinated rainbow trout.

Significantly higher antibody levels in plasma were detected in vaccinated fish compared with mock-vaccinated fish.

Injection vaccination did not trigger specific antibody production in the skin mucus. Significantly higher survival of i.p. vaccinated fish compared with non-vaccinated fish was observed during the challenge.

The results suggest that mineral oil-based injectable vaccines containing formalin- or heat-inactivated virulent cells of F. psychrophilum effectively triggered specific antibody production and protected the fish against bacterial cold water disease.


Source: Madetoja, J, Lönnström, L-G, Björkblom, C, Uluköy, G, Bylund, G, Syvertsen, C, Gravningen, K, Norderhus, E-A & Wiklund, T (2006): Efficacy of injection vaccines against Flavobacterium psychrophilum in rainbow trout, Oncorhynchus mykiss (Walbaum). In: Journal of Fish Diseases 29 (1), 9-20.











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SMALL ANIMAL PRACTICE

Computed tomographic findings in dogs infected with Crenosoma vulpis
Crenosoma vulpis is a nematode lungworm found in wild and domestic canids in some parts of North America and Europe. Reported radiographic findings are nonspecific and consist of a combination of bronchial and interstitial changes of variable severity. This retrospective, case series study aimed to describe thoracic computed tomographic (CT) findings for a group of dogs with confirmed crenosomosis. Selection criteria were presentation with a chronic cough during the period of January 2016 to February 2017, evaluation by thoracic CT, and final diagnosis of C. vulpis infection based on bronchoscopic findings, bronchoalveolar lavage fluid analysis, and quantitative polymerase chain reaction.

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