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Effects of medetomidine and medetomidine-butorphanol combination on tear production
If a xylazine-ketamine combination is used, everybody is used to apply artificial tears. But how do you manage this with the very popular medetomidine or medetomidine-butorphanol combination? It is also indicated, as this very interesting new study shows!!

Medetomidine is a commonly used sedative in veterinary medicine whether administered alone or in combination with an opioid such as butorphanol.

There are no previous studies that look at the effects of this drug on sequential Schirmer tear test (STT) 1 readings in dogs, including effects on tear production after reversal of the drug.

The present study looked at two groups of 10 dogs each that were sedated with intravenous medetomidine or a combination of medetomidine and butorphanol.

All dogs had tear readings taken presedation, 15 min postsedation, and 15 min after reversal of medetomidine with atipamezole.

Results revealed that intravenous sedation with medetomidine and medetomidine-butorphanol in dogs with no history of ophthalmic disease and presedation STT 1 readings above 15 mm/min, causes a significant decrease in tear production that is measurable at 15 min postsedation.

Readings returned to near presedation values within 15 min postreversal in most cases.

It is therefore recommended that all eyes be treated with a tear substitute from the time the sedative is given until at least 15 min after reversal.




Source: Sanchez, R. F., Mellor, D. & Mould, J. (2006): Effects of medetomidine and medetomidine-butorphanol combination on Schirmer tear test 1 readings in dogs. In: Veterinary Ophthalmology 9 (1), 33-37.





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SMALL ANIMAL PRACTICE

Computed tomographic arthrography of the canine shoulder joint members
The aim of this retrospective, methods comparison study was to assess the diagnostic utility of computed tomographic arthrography in the assessment of various intraarticular shoulder pathologies in dogs in comparison with survey computed tomography (CT), using arthroscopic examination as the reference standard. Computed tomography, computed tomographic arthrography, and arthroscopic findings of 46 scapulohumeral joints of dogs with forelimb lameness were reviewed retrospectively.

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