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Efficacy and Safety of Preoperative Etodolac and Butorphanol in Dogs
Ovariohysterectomy is one of the most performed surgeries in small animal medicine. Nearly everybody has `his` or `her` preferred anesthesia including premedication. But this brandnew article gives interesting alternatives in premedication.

Eighteen dogs undergoing ovariohysterectomy were premedicated with etodolac, butorphanol, or their combination.

Various parameters, such as blood pressure, isoflurane requirements, behavioral pain scores, plasma cortisol concentration, plasma glucose concentration, and mucosal bleeding time, were assessed.

The integrated plasma cortisol values were significantly lower in the etodolac and etodolac with butorphanol groups.

Dogs receiving etodolac and butorphanol had the lowest behavioral pain scores from extubation until the end of monitoring.

Isoflurane concentration over time (area under the curve), buccal mucosal bleeding time, and indices of renal function were not significantly different among the treatment groups.





Source: Tomohito Inoue, Jeff C. Ko, Ronald E. Mandsager, Mark E. Payton, David S. Galloway, Douglas N. Lange (2006): Efficacy and Safety of Preoperative Etodolac and Butorphanol Administration in Dogs Undergoing Ovariohysterectomy. In: Journal of the American Animal Hospital Association 42:178-188 (2006)



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SMALL ANIMAL PRACTICE

Reference intervals for blood parameters in Shetland Sheepdogsmembers
Several breeds have physiological peculiarities that induce variations in reference intervals (RIs) compared with the general canine population. Shetland sheepdogs (SSs) are reported to be more predisposed to different diseases (eg, hyperlipidemia, gallbladder mucocele, and hypothyroidism). Consequently, a breed‐specific approach is more often required. Thus, the aim of this study was to determine whether the RIs of the general canine population could be applied to that of SSs, and to generate breed‐specific RIs, where appropriate.

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