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Uveal metastasis of a primary pulmonary adenocarcinoma
Primary malignant pulmonary neoplasias are not too common in dogs, and surely it is not common for them to metastasize in eye, brain and adrenal gland. A very interesting case report of a dog presented with seizures!

A 10-year-old male Briard dog was presented because of listlessness, abnormal gait, fever, inappetence, and seizures.

A non-pigmented growth was observed in the ventral quadrant of the left iris.

Thoracic radiographs revealed multiple pulmonary metastases and the owner opted for killing.

On necropsy, lung masses and nodules in left iris, right adrenal medulla, and brain were detected.

Histologically the primary tumour was diagnosed as pulmonary adenocarcinoma with predominant solid pattern. Metastases to regional lymph nodes, uvea, adrenal medulla, and brain were recognized.

The metastatic behaviour resembled that occurring in humans. To the authors` knowledge, this is the first report of a pulmonary adenocarcinoma with metastasis to the uvea in a dog.



Source: Castellano, M. C., Massone, A. R. & Idiart, J. R. (2006): Primary Pulmonary Adenocarcinoma Metastatic to the Uvea, Brain and Adrenal Gland in a Dog. In: Journal of Veterinary Medicine Series A 53 (4), 194-197.




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