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Do probiotic bacteria improve the effect of an elimination diet in dogs?
A very important question which is commonly asked by owners of dogs with food responsive diarrhea - Is elimination diet alone sufficient, or should probiotic bacteria be recommended? A very informative recently published study has the answer...

We evaluated whether a probiotic supplementation in dogs with food responsive diarrhoea (FRD) has beneficial effects on intestinal cytokine patterns and on microbiota.

Twenty-one client-owned dogs with FRD were presented for clinically needed duodeno- and colonoscopy and were enrolled in a prospective placebo (PL)-controlled probiotic trial.

Intestinal tissue samples and faeces were collected during endoscopy. Intestinal mRNA abundance of interleukin (IL)-5, -10, -12p40 and -13, tumour necrosis factor-á, transforming growth factor-â1 and interferon (IFN)-ã were analysed and numbers of Lactobacillus spp., Bifidobacterium spp., Enterococcus spp. and Enterobacteriaceae and supplemented probiotic bacteria were determined in faeces.

The Canine Inflammatory Bowel Disease Activity Index, a scoring system comprising general attitude, appetite, faecal consistency, defecation frequency, and vomitus, decreased in all dogs (p < 0.0001).
Duodenal IL-10 mRNA levels decreased (p = 0.1) and colonic IFN-ã mRNA levels increased (p = 0.08) after probiotic treatment.

Numbers of Enterobacteriaceae decreased in FRD dogs receiving probiotic cocktail (FRDPC) and FRD dogs fed PL (FRDPL) during treatment (p < 0.05), numbers of Lactobacillus spp. increased in FRDPC after when compared with FRDPC before (p < 0.1).

One strain of PC was detected in five of eight FRDPC dogs after probiotic supplementation.

In conclusion, all dogs clinically improved after treatment, but cytokine patterns were not associated with the clinical features irrespective of the dietary supplementation.


Source: Sauter, S. N., Benyacoub, J., Allenspach, K., Gaschen, F., Ontsouka, E., Reuteler, G., Cavadini, C., Knorr, R. & Blum, J. W. (2006): Effects of probiotic bacteria in dogs with food responsive diarrhoea treated with an elimination diet*. In: Journal of Animal Physiology and Animal Nutrition 90 (7-8), 269-277.




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SMALL ANIMAL PRACTICE

Radiation Therapy for the Treatment of Sialocele in Dogs
Sialocele is a collection of saliva that has leaked from a damaged salivary gland or duct and is surrounded by granulation tissue. Surgery is the recognized first-line treatment. Recurrence rate after surgery is 5–14%. Salivary gland tissue is very sensitive to radiation therapy - so the aim of this new study was to characterize response rate and clinical course of dogs with sialocele treated with RT and to determine a starting dose for clinical use.

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