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Histomorphometry of Fragmented Medial Coronoid Process in Dogs
A fragmented processus coronoideus medialis is commonly seen in small animal practice, especially young male dogs of large or giant breeds are affected. Less is known about the question if fatigue microdamage is associated with fragmented medial coronoid process (FMCP).
This brandnew study compares affected and normal coronoid processes. Very interesting!

Thirty-eight dogs were admitted for subtotal coronoid ostectomy as treatment for FMCP. Surgical specimens of medial coronoid process (MCP) were retrieved from treated dogs. Normal MCP were collected from 5 age- and breed-matched dogs and 2 age-matched research beagles that were euthanatized for reasons other than elbow disease.

Methods: MCP specimens from affected elbows were classified into 4 groups based on disease severity.

Specimens were bulk-stained for microdamage using 1% basic fuchsin, embedded in polymethylmethacrylate and sectioned at 130 ìm.

Specimens were evaluated using epifluorescent microscopy (425–440 excitation, 475 nm barrier filter) for diffuse damage (D.DX), osteocyte loss, and porosity.

Cartilage thickness was evaluated using bright field microscopy. Qualitative observations were also made.

Results: MCP specimens from affected elbows had increased D.Dx, increased osteocyte loss, and greater porosity than normal groups.

Specimens classified as severe FMCP (Classes 3, 4) had the most fatigue microdamage. Some Class 1 specimens, defined as having no visible fissuring of the articular cartilage (AC), had large microcracks in trabecular bone.

Conclusions: Accumulation of subchondral fatigue microdamage, is associated with MCP fragmentation. Fissuring occurs in the subchondral bone before gross fibrillation of articular cartilage develops.

Accumulation of fatigue microdamage in the MCP is important in the pathogenesis of FMCP. The underlying cause of this microdamage accumulation must be identified before treatment plans that will prevent further osteoarthritis of the elbow joint can be designed.


Source: DANIELSON, KELSON C., FITZPATRICK, NOEL, MUIR, PETER & MANLEY, PAUL A. (2006): Histomorphometry of Fragmented Medial Coronoid Process in Dogs: A Comparison of Affected and Normal Coronoid Processes. In: Veterinary Surgery 35 (6), 501-509.




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SMALL ANIMAL PRACTICE

Reference intervals for blood parameters in Shetland Sheepdogsmembers
Several breeds have physiological peculiarities that induce variations in reference intervals (RIs) compared with the general canine population. Shetland sheepdogs (SSs) are reported to be more predisposed to different diseases (eg, hyperlipidemia, gallbladder mucocele, and hypothyroidism). Consequently, a breed‐specific approach is more often required. Thus, the aim of this study was to determine whether the RIs of the general canine population could be applied to that of SSs, and to generate breed‐specific RIs, where appropriate.

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