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Surgery alone or surgery plus chemotherapy in feline injection-site lymphosarcomas?
A very important question, since these neoplasias are seen on a regular base by every small animal practitioner. This very interesting study compares both therapeutic approaches on 69 cats - with a very surprising result!

Sixty-nine cats were treated for injection-site sarcomas at the Veterinary Teaching Hospital of Grugliasco, Turin (Italy).

The animals were divided into two subgroups: those subjected to four doxorubicin cycles combined with radical surgical excision 10 days after the second chemotherapy cycle (group A, 49 cats) or those treated with surgery alone (group B, 20 cats).

Each cat was monitored for lung metastasis and local recurrence.

In group A, 28 cats were alive at the end of the follow-up period. In this group, the recurrence rate was 40.8% while lung metastasis occurred in 12% of cats.

In group B, eight animals were alive at the end of the follow-up period, while the rates of recurrence and metastasis were 35% and 10%.

Neither the median disease-free interval nor the median overall survival was reached in either group. Moreover, there were no statistically significant differences between the two groups.



Source: Martano M, Morello E, Ughetto M, Iussich S, Petterino C, Cascio P, Buracco P. (2005): Surgery alone versus surgery and doxorubicin for the treatment of feline injection-site sarcomas: a report on 69 cases. In: Vet J. 2005 Jul;170(1):84-90.



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SMALL ANIMAL PRACTICE

Determining the origin of hepatic masses in dogs by CTmembers
Can CT scans diagnose the anatomical origin of hepatic masses? A very interesting question! The objective of this study was to identify CT features of canine hepatic masses that could be used to determine their divisional or lobar origin.

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