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Mucinous mammary carcinoma in the cat
Mammary tumours are rare in the cat, but when they occur, they are malignant in most of the cases. This brandnew report describes a special mammary tumour: the mucinous carcinoma. Very informative!

Mucinous carcinoma of the mammary gland is a rare tumor characterized by excessive mucin production.

In human and canine pathology, the diagnosis of mucinous carcinoma is based on the demonstration of an epithelial phenotype of mucus-producing cells and periodic acid–Schiff (PAS)-diastase positivity of the mucin.

The histologic and immunohistologic characteristics of feline mucinous mammary carcinoma were examined.

Of 656 cases of feline mammary neoplasms and dysplasias, 3.2% were found to be mucin-producing tumors. Cytokeratin 19 (16 cases positive, 4 heterogenous, and 1 negative) and vimentin (15 cases positive, 2 heterogenous, and 4 negative) expression were examined, and the mucin produced was alcian blue positive.

PAS-diastase staining was variable (38.1%). Based on these findings, mucinous mammary carcinoma in the cat varies significantly from the human and canine varieties and alcian blue is the prominent stain in the diagnosis of feline mucinous carcinoma.



Source: G. Sarli, B. Brunetti and C. Benazzi (2006): Mammary Mucinous Carcinoma in the Cat. In: Vet Pathol 43:667-673 (2006)




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SMALL ANIMAL PRACTICE

3 Serological Tests for Early Detection Of Leptospira-specific Antibodies
Leptospirosis in dogs is a disease of global importance. Early detection and appropriate therapeutic intervention are necessary to resolve infection and prevent zoonotic transmission. However, its diagnosis is hindered by nonspecific clinical signs and lack of rapid diagnostic tests of early infection. Recently, 2 rapid point-of-care tests (WITNESS Lepto [WITNESS Lepto, Zoetis LLC, Kalamazoo, MI, USA] and SNAP Lepto [SNAP Lepto, IDEXX Laboratories, Westbrook, ME, USA]) for detection of Leptospira-specific antibodies in canine sera were developed. This recently online published article compares three systems for early diagnosis.

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