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Helicobacter pylori-like bacterium in pigs
Helicobacter pylori is blamed for a variety of gastrointestinal symptoms in humans and is also diagnosed in dogs. A related bacterium can cause severe gastroesophageal ulcers in piglets depending from the diet, as this very informative recently published study illustrates.

Groups of gnotobiotic piglets were orally inoculated at 3 days of age with either Helicobacter heilmannii (Hh) or a newly described porcine-origin gastric Helicobacter pylori (Hp)-like bacterium. Three Hh-infected and 6 porcine Hp-like–infected swine were fed a milk replacement diet containing 5–10% (v/v) sterile corn syrup as a dietary source of fermentable carbohydrate.

None of the piglets infected with Hh and supplemented with corn syrup developed gastric mucosal ulcers; 2 developed small erosive lesions in the pars esophagea.

In contrast, all 6 dietary carbohydrate-supplemented Hp-like–infected swine developed severe gastroesophageal ulcers; 1 of these ex-sanguinated into the stomach and died before the end of the experiment.

Four of these 6 piglets had grossly evident partially digested blood in the intestinal lumens, indicative of bleeding into the gastrointestinal tract from the stomach.

These data suggest that a high carbohydrate diet and gastric colonization by porcine Hp-like bacteria facilitate development of clinically significant gastroesophageal ulcers.



Source: S. Krakowka and J. Ellis (2006): Reproduction of Severe Gastroesophageal Ulcers (GEU) in Gnotobiotic Swine Infected with Porcine Helicobacter pylori-like Bacteria. In: Vet Pathol 43:956-962 (2006)





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SWINE PRACTICE

Exposure of pigs to lead from contaminated zinc oxide members
High levels of lead, up to 3.3 mg/kg fresh weight, were detected in pig liver in Western Australia at the beginning of 2008. This followed the detection of lead at above the maximum level (ML) in a pig liver through the National Residue Survey (NRS). The contamination source was traced back to a zinc oxide feed additive used early post-weaning that contained in excess of 8% lead. The aim of this study was the confirmation of the source of lead contamination was obtained by comparing lead isotope ratios for the zinc oxide and the pig livers.


  • Conjugated Linoleic Acid and Growth Performance and Losses of Pigletsmembers
  • Introduction of PRRSV via Boar Semen into a PRRSV-Free Countrymembers
  • Dorsal black skin necrosis in a pot-bellied pigmembers
  • Effect of pharmacological interventions between conception and birth in swinemembers
  • Update to PCV2-virus and associated diseasesmembers
  • Brucellosis and leptospirosis in feral pigs in Australiamembers
  • Comparison of nutritive value of different diet ingredients for growing pigsmembers
  • Apoptosis of T- and B-lymphocytes in PRRSV-infectionsmembers
  • Zearalenone - kinetics and metabolism in young female pigsmembers
  • Comparison of five commercial extenders for boar semenmembers
  • Muscle fiber characteristics as additional breeding selection criteria in pigsmembers
  • Mast Cells in the Uterus of Pregnant Meishan Pigsmembers


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