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High incidence of malignancy in chest wall tumours of dogs
Investigators from Cambridge reviewed 46 dogs with chest wall tumours: 43 of them were malignant, and surgery improved the outcome significantly. What tumours were most common, and what should be considered before surgical excision?

43 out of 46 tumours were malignant; five had metastases apparent at the time of presentation, five more had metastases discovered intraoperatively. Surgical resection of the tumours was associated with a significantly better outcome than conservative management.

The median survival times after surgery for dogs with osteosarcoma was 17 weeks, for dogs with fibrosarcoma it was 26 weeks and for dogs with chondrosarcoma it was 250 weeks.

En bloc excision of primary tumours affecting the chest wall was associated with minimal morbidity, but long-term survival was limited by distant metastases, primarily to the lungs. The tumours recurred in only three dogs.

Early, radical surgical excision is recommended in the management of tumours of the chest wall. The prognosis depends on the histologic type of tumour and a histological diagnosis is mandatory before excision.

Source: S. J. Baines, S. Lewis, MA, R. A. S. White (2002): Primary thoracic wall tumours of mesenchymal origin in dogs: a retrospective study of 46 cases. In: The Vet Record, 150:11, pp 335-339 (16th March 2002)






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SMALL ANIMAL PRACTICE

Novel intratumoral therapy in canine transmissible venereal tumour
Canine transmissible venereal tumour (CTVT) is a naturally occurring contagious neoplasm of dogs located mainly on the external genitalia of both sexes. The course of vincristine chemotherapy, the most effective and practical therapy, is affected by the immune status of the host. The aim was to investigate recombinant human interferon alpha‐2a (rhIFNα‐2a) and vincristine for treatment of CTVT.

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