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Positive intraoperative cultures from canine total hip replacements
A very interesting study which detected positive cultures in 11 out of 27 patients undergoing total hip replacements (THR). It sounds alarming but the results regarding short- and long-term-success are surprising.

The results of closing intraoperative cultures from 27 canine total hip replacements (THR) were reviewed.

The relationship between these culture results and presurgical and surgical factors, and the short- and long-term success of THR were assessed.

Eleven out of 27 cases had a positive culture, but none of these 11 cases were diagnosed with periprosthetic infection at follow-up examination.

The duration of the clinical signs of hip disease prior to THR was significantly greater for those cases with a positive culture (P=0.034).

The incidence of positive cultures was not related to surgical success.



Source: Karla C.L. Lee, Amy S. Kapatkin (2002): Positive Intraoperative Cultures and Canine Total Hip Replacement: Risk Factors, Periprosthetic Infection, and Surgical Success. In: Journal of the American Animal Hospital Association 38:271-278 (2002)




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SMALL ANIMAL PRACTICE

Variability of SDMA in apparently healthy dogsmembers
Symmetric dimethylarginine (SDMA) is a screening tool for early kidney dysfunction and monitoring treatment in cases of chronic kidney disease (CKD). There are no current studies describing the suitability of this test for use with published population‐based reference intervals. The objectives of this study were to determine the components of biological variability, the index of individuality (IOI), the critical difference between sequential measurements (CD) and the number of measurements required to assess the homeostatic set point (HSP), for both SDMA and serum creatinine (sCr), in apparently healthy dogs.

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