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PCR-tests in cats with plasmacytic pododermatitis
Plasmacytic pododermatitis is an unique disease of cats whose pathogenesis is not fully clear. In this study, DNA of various infectious agents (including bacteria, viruses and toxoplasma) were tested via PCR. Very interesting!

Sections of 14 skin biopsies of cats with plasmacytic pododermatitis and a clinical follow-up of 12–36 months were stained with a polyclonal anti-Mycobacterium bovis (Bacille Calmette-Guerin = BCG) antibody cross-reactive to a broad spectrum of fungi and bacteria.

All sections were negative for organisms within the actual footpad tissue with the anti-BCG antibody stains.

Polymerase chain reaction (PCR) assays that amplify the DNA of Bartonella spp., Ehrlichia spp., Anaplasma phagocytophilum, Chlamydophila felis, Mycoplasma spp., Toxoplasma gondii, and feline herpesvirus 1 (FHV-1) were applied to tissue digests. DNA of those pathogens assessed was not amplified from tissue.



Source: S. V. Bettenay, M. R. Lappin and R. S. Mueller (2007): An Immunohistochemical and Polymerase Chain Reaction Evaluation of Feline Plasmacytic Pododermatitis. In: Vet Pathol 44:80-83 (2007)




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SMALL ANIMAL PRACTICE

Shock index in identifying acute blood loss in healthy dogs
Does the shock index (SI) increase following blood donation and is it a more sensitive assessment of acute blood loss as heart rate (HR), blood pressure, and plasma Lactate? An interesting question! 20 client-owned clinically normal dogs were enrolled in this prospective study.

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  • RET-He to diagnose iron-deficient erythropoiesis in dogsmembers
  • Hypertriglyceridemia-Associated Proteinuria in Miniature Schnauzersmembers
  • Gastrointestinal dysmotility disorders in critically ill animalsmembers
  • Disorder of sex development in a cat with chromosome mosaicism members
  • Generalized discoid lupus erythematosus in dogs members
  • Epidermolysis bullosa acquisita in dogsmembers
  • Chiari-Like Malformation and Syringomyelia in American Brussels Griffon Dogsmembers
  • Efficacy and Potential Complications of Transjugular Liver Biopsymembers
  • Hypomagnesemia in Brachycephalic Dogsmembers
  • Comparison of two minimally invasive techniques for liver biopsy members
  • Topical aqueous sirolimus and the tear production members


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