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Malignant ameloblastic fibro-odontoma in a Collie (case report)
An old dog which is presented with a swelling of the face - the first differential diagnosis is without doubt a teeth problem, the second epulis. But both is not the case: it is a highly malignant tumor which already metastatasized in various organs. A very informative case report from Japan!

An 11-year-old male Collie was presented with a swelling of the face caused by tumor masses arising from the gingiva.

Postmortem examination revealed metastases to the lymph nodes, lung, liver, and orbital cavity. Histologically, the tumor represented a combination of fibrosarcomatous proliferation, pulpal mesenchyme, and undifferentiated odontogenic epithelium, with a follicular or plexiform growth pattern.

In addition, the follicular areas of the tumor showed a biphasic character, and there were numerous apoptotic cells in plexiform areas.

Furthermore, acidophilic material resembling dysplastic dentine or enamel matrix was observed in the metastatic lesion in the lung.

Based on the histological characters, the present case was diagnosed as malignant ameloblastic fibro-odontoma.

This study is the first known description of a possible malignant ameloblastic fibro-odontoma in a dog with metastasis to distant organs.



Source: Ueki H, Sumi A, Takaishi H, Ito H, Oyamada T, Yoshikawa H. (2004): Malignant ameloblastic fibro-odontoma in a dog. In: Vet Pathol. 2004 Mar;41(2):183-5.



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SMALL ANIMAL PRACTICE

Patient-specific facemask to facilitate brain biopsymembers
The objective of this pilot study was to describe the application and first preliminary data of a novel MRI and CT compatible patient-specific facemask for stereotactic brain biopsy of intracranial lesions in dogs. Five client-owned dogs presenting for neurological deficits consistent with forebrain disease were included in the study. All dogs had MRI findings consistent with an intracranial lesion. But biopsies in this region are not easy to obtain. Does an individual face mask help?

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