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Pseudothrombocytopenia (PTCP) secondary to EDTA in dogs
This phenomenon has already been describes in other species like horses and pigs and it should be considered in dogs with moderate thrombocytopenia and no clinical bleeding tendency. A very informative publication!

This type of pseudothrombocytopenia is not a pathological process by itself, but it can be clinically significant if diagnostics and medical treatments are initiated based on the reported thrombocytopenia.

Platelet clumping occurs with EDTA-dependent PTCP, resulting in inaccurate hematology analyzer platelet concentrations.

A nontraumatic venipuncture may be sufficient to obtain an accurate platelet count.

However, rare cases in the dog may require blood drawn into a different anticoagulant, such as sodium citrate, to help discriminate a true thrombocytopenia from PTCP.



Source: Tamara B. Wills, K. Jane Wardrop (2008):Pseudothrombocytopenia Secondary to the Effects of EDTA in a Dog. In: Journal of the American Animal Hospital Association 44:95-97 (2008)






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SMALL ANIMAL PRACTICE

Microbiota of traumatic, open fracture wounds and the mechanism of injury
Open fractures are characterized by disruption of the skin and soft tissue, which allows for microbial contamination and colonization. Preventing infection‐related complications of open fractures and other acute wounds remains an evolving challenge due to an incomplete understanding of how microbial colonization and contamination influence healing and outcomes. Culture‐independent molecular methods are now widely used to study human‐associated microbial communities without introducing culture biases. This recently online published study describes the fascinating association between the mechanism of injury and the microbiota of the wounds.

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