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Detection of osseous metastasis in canine osteosarcoma with nuclear scintigraphy
Bayer 2274.jpg Picture: © Bayer Animal Health
In this retrospective study on more than 300 dogs the use of nuclear scintigraphy with 99mTc-HDP in determining the rate of secondary sites of osseous malignancy at initial presentation in dogs with osteosarcoma was evaluated - a diagnostic method which is commonly used in human medicine but not in animals.

Radiographs of suspicious secondary lesions were reviewed and placed into four separate categories: benign lesions; no lesion seen on radiographs; subtle radiographic changes suggestive of, but not conclusive for, metastasis; and metastatic lesions highly suspected on radiographs. Three hundred and ninety-nine dogs were evaluated by technetium nuclear scanning for suspected osteosarcoma.

Three hundred and twenty-six of 399 dogs (82%) had only one apparent site on the nuclear scan, whereas 72 dogs (18%) had more than one suspicious site on the nuclear scans. Highly suspected secondary metastatic lesions were detected by nuclear scans in 7.8% of cases.

Although interpretation of nuclear scans is subjective, this study showed a 7.8% chance of detecting unsuspected osseous metastasis with nuclear scans in canine osteosarcoma patients on initial presentation.

Source: Jankowski, M. K., Steyn, P. F., Lana, S. E., Dernell, W. S., Blom, C. M., Uhrig, J. L., Lafferty, M. & Withrow, S. J. (2003): Nuclear scanning with 99mTc-HDP for the initial evaluation of osseous metastasis in canine osteosarcoma. In: Veterinary and Comparative Oncology 1 (3), 152-158.




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SMALL ANIMAL PRACTICE

Reference intervals for blood parameters in Shetland Sheepdogsmembers
Several breeds have physiological peculiarities that induce variations in reference intervals (RIs) compared with the general canine population. Shetland sheepdogs (SSs) are reported to be more predisposed to different diseases (eg, hyperlipidemia, gallbladder mucocele, and hypothyroidism). Consequently, a breed‐specific approach is more often required. Thus, the aim of this study was to determine whether the RIs of the general canine population could be applied to that of SSs, and to generate breed‐specific RIs, where appropriate.

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