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Serum magnesium abnormalities in hospitalized cats
Is an alteration of the serum magnesium concentration a serious problem in very sick cats, and how often does it occur? A prospective study at the intensive care unit (ICU) of the Cornell University Hospital for Animals evaluated 57 cats.

Data were collected and analyzed to determine the following: prevalence and incidence of [Mg2+](s) abnormalities, medical disorders associated with altered [Mg2+](s), association of altered [Mg2+](s) with other electrolyte abnormalities, length of hospitalization for cats with abnormalities of [Mg2+](s) versus those with normal [Mg2+](s), and survival of cats with abnormal [Mg2+](s) versus those with normal [Mg2+](s).

The point prevalence of magnesium abnormalities was 26%, the period prevalence was 46%, and the cumulative incidence was 23%.

Hypermagnesemia was associated with abnormalities of serum potassium (P = .04) and phosphate (P = .01) concentrations.
Abnormalities of [Mg2+](s) were not associated with abnormal serum concentrations of Na+, Ca2+, or Cl-. On admission, hypomagnesemia was detected in cats with gastrointestinal, endocrine, and other disorders; hypermagnesemia was detected only in cats with renal disease, obstructive Uropathy, or neoplastic disease.

The median hospital stay for cats that developed abnormal [Mg2+](s) after admission was longer than for cats that remained nor momagnesemic (5 versus 4 days, respectively; P = .03). Despite the longer hospital stay, the survival of these cats was lower than that of normomagnesemic cats (54 versus 77%; P = .05).

When all cats were considered, the survival of cats with abnormal [Mg2+](s) also was decreased compared with normomagnesemic cats (62 versus 81%; P = .05).

We conclude that abnormalities of [Mg2+](s) may affect morbidity and mortality of affected cats.


Source: J Toll, H Erb, N Birnbaum, T Schermerhorn (2002): Prevalence and incidence of serum magnesium abnormalities in hospitalized cats. In:
Journal of Veterinary Internal Medicine, 2002, Vol 16, Iss 3, pp 217-221




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SMALL ANIMAL PRACTICE

Reference intervals for blood parameters in Shetland Sheepdogsmembers
Several breeds have physiological peculiarities that induce variations in reference intervals (RIs) compared with the general canine population. Shetland sheepdogs (SSs) are reported to be more predisposed to different diseases (eg, hyperlipidemia, gallbladder mucocele, and hypothyroidism). Consequently, a breed‐specific approach is more often required. Thus, the aim of this study was to determine whether the RIs of the general canine population could be applied to that of SSs, and to generate breed‐specific RIs, where appropriate.

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