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Fipronil spray in canine scabies
A variety of drugs is known to be effective in canine scabies. A group from Greece did a field trial with fipronil spray which was used on a weekly basis (manufacturers´ recommendation: every 4-12 weeks) to evaluate if it was effective against Sarcoptes scabiei variatio canis.

Twelve dogs naturally infested with S. Scabiei were included in the trial. Diagnosis was based on clinical signs, skin scrapings and/or serology.

All the dogs were treated with a 0.25% fipronil spray, once weekly, for four consecutive weeks, using a total of 12 to 39 mL/kg of spray.

Pruritus and skin lesions disappeared, respectively, seven to 66 days and 14-71 days after the beginning of the treatment.

No relapses occurred during the three to four-month follow-up period.

Three dogs were kept under observation for a further eight to 12-month period with no relapses witnessed.
Of the nine dogs that had been seropositive at the beginning of the study, only two out of six were found to be seronegative when retested three to four months after the end of the treatment.


Source: AF Koutinas, MN Saridomichelakis, N Soubasis, S Bornstein, CK Koutinas (2001): Treatment of canine sarcoptic mange with fipronil spray: A field trial. In: Australian Veterinary Practitioner, 2001, Vol 31, Iss 3, pp 115+




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SMALL ANIMAL PRACTICE

Long-term outcome of dogs with primary immune-mediated thrombocytopeniamembers
Primary immune‐mediated thrombocytopenia (IMTP) is a life-threatening condition which is occasionally seen in dogs. Also many of them respond to intensive therapy, the incidence of relapse may be underestimated. The objectives of this new study were to determine the incidence of relapse after discharge from the hospital in dogs with a diagnosis of presumed primary immune‐mediated thrombocytopenia, risk factors associated with relapse and whether or not indefinite use of immunosuppressive medication influences risk of relapse.

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