Home
http://www.virbac.fr/ http://www.boehringer-ingelheim.com/ http://www.novartis.com/ http://www.animalhealth.bayerhealthcare.com/
vetcontact
Vetrinär
Tiermedizin
  WELCOME  
vetcontact
Vetrinär
Tiermedizin
  Privacy Policy  
  Home  
  Login / Newsletter  
vetcontact
Vetrinär
Tiermedizin
  CONTACTS  
vetcontact
Vetrinär
Tiermedizin
  Classifieds  
  New Products  
  VetCompanies  
  VetSchools  
vetcontact
Vetrinär
Tiermedizin
  PROFESSION  
vetcontact
Vetrinär
Tiermedizin
  Edutainment  
  VetAgenda  
  Presentations  
  Posters  
  ESAVS  
  Specialisation  
vetcontact
Vetrinär
Tiermedizin
  INSIGHT  
vetcontact
Vetrinär
Tiermedizin
  Congress News  
  Picture Galleries  
vetcontact
Vetrinär
Tiermedizin
  PRODUCTS  
vetcontact
Vetrinär
Tiermedizin
  Bayer  
  Boehringer Ing.  
  Novartis  
  Virbac

 
  Simply book for less...  
    

Bovine    Equine    Small Animal Practice    Swine Practice    Articles    Vetjournal    
deutsch english español polski francais
Home / WELCOME / Archiv / Small Animal Practice /     
 
Acepromazine before opioids lowers incidence of vomiting
Opioid-induced vomiting is a well-known phenomenon. In a randomized prospective clinical study, a group from Florida evaluated the anti-emetic properties of acepromazine in dogs receiving opioids as pre-anesthetic medication.

Effects of acepromazine on the incidence of vomiting associated with opioid administration in dogs
Alexander Valverde DVM, DVSc, Diplomate ACVA, Shauna Cantwell DVM, MVSc, Diplomate ACVA, Jorge Hernández MVZ, MPVM, PhD & Celeste Brotherson DVM

Abstract

One hundred and sixteen dogs (ASA I or II), admitted for elective surgical procedures were included. The dogs were a mixed population of males and females, purebreds and mixed breeds, 0.25-13.4 years of age, weighing 1.8-57.7 kg.

In this prospective clinical trial the dogs were randomly assigned to one of three groups. All groups received acepromazine (0.05 mg kg1 intramuscularly (IM)). Group I received acepromazine 15 minutes prior to opioid administration. Group II received acepromazine in combination with the opioid. Group III received acepromazine 15 minutes after opioid administration. One of three different opioids was administered IM to each dog: morphine sulfate at 0.5 mg kg1; hydromorphone hydrochloride at 0.1 mg kg1; or oxymorphone hydrochloride at 0.075 mg kg1.

Dogs receiving acepromazine before the opioid (group I) had a significantly lower incidence of vomiting (18%) than dogs in groups II (45%) and III (55%).

The degree of sedation was significantly lower in the dogs receiving the combination of acepromazine and the opioid (group II) than in dogs receiving the opioid as the first drug (group III).

Acepromazine administered 15 minutes before the opioid lowers the incidence of vomiting induced by opioids.

Source: Valverde, Alexander, Cantwell, Shauna, Hernández, Jorge & Brotherson, Celeste (2004): Effects of acepromazine on the incidence of vomiting associated with opioid administration in dogs. In: Veterinary Anaesthesia and Analgesia 31 (1), 40-45.



Tell a friend   |   Print version   |   Send this article

SMALL ANIMAL PRACTICE

Microbiota of traumatic, open fracture wounds and the mechanism of injury
Open fractures are characterized by disruption of the skin and soft tissue, which allows for microbial contamination and colonization. Preventing infection‐related complications of open fractures and other acute wounds remains an evolving challenge due to an incomplete understanding of how microbial colonization and contamination influence healing and outcomes. Culture‐independent molecular methods are now widely used to study human‐associated microbial communities without introducing culture biases. This recently online published study describes the fascinating association between the mechanism of injury and the microbiota of the wounds.

  • Variability of SDMA in apparently healthy dogsmembers
  • Bioavailability of suppository acetaminophen in dogsmembers
  • Computed tomographic lymphography for lymph node staging in dogs with malignant tumors members
  • Characterization of ocular melanosis-affected canine melanocytesmembers
  • Nasopharyngeal sialoceles in brachycephalic dogsmembers
  • Enterococcus faecium SF68 on serum cobalamin and folate concentrationsmembers
  • Gastrointestinal eosinophilic sclerosing fibroplasia limited to the mesentery in a catmembers
  • Ion acid-base disturbances and associated mortality in dogsmembers
  • First description of ultrasonic bone curette in canine otic surgerymembers
  • Staining hair samples with a modified Wright-Giemsa stain to diagnose feline dermatophytosismembers
  • Oral extended release hydrocodone as analgesia after TPLOmembers
  • 25OH vitamin D3 serum concentration in dogs with acute polyradiculoneuritismembers


  • [ Home ] [ About ] [ Contact / Request ][ Disclaimer ]

    Copyright © 2001-2016 VetContact GmbH
    All rights reserved