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CT-guided fine needle aspiration and tissue-core biopsy of bone lesions
Free-hand computed tomography (CT)-guided biopsy is a common and accurate method to obtain a tissue sample in human medicine. Only a few reports of this technique exist in veterinary medicine. In this Italian-Swiss study, 23 small animals were included and received either a FNA or a tissue core biopsy.

21 dogs and two cats underwent a free-hand CT-guided tissue-core biopsy (17 animals) or fine-needle aspiration (six animals) of a bone lesion. Two out of 17 tissue-core samples were also cultured.

All 17 tissue-core biopsy samples were diagnostic (accuracy of 100%). Five out of six aspirates were diagnostic (accuracy of 83.3%). The overall accuracy was 95.7%. In one aspirate, cytologic quality was insufficient containing only blood.

No major complications were encountered. Fourteen neoplastic, two infectious and six benign lesions were diagnosed.
CT examination after intravenous contrast medium added useful information to avoid large vessels and to biopsy-viable tissue.

Free-hand CT-guided tissue-core biopsy and aspiration appears to be a safe and very accurate procedure for use in the diagnosis of bone-associated diseases in small animals.

Source: Vignoli, Massimo, Ohlerth, Stefanie, Rossi, Federica, Pozzi, Luigi, Terragni, Rossella, Corlazzoli, Daniele & Kaser-Hotz, Barbara (2004): Computed tomography-guided fine-needle aspiration and tissue-core biopsy of bone lesions in small animals. In: Veterinary Radiology & Ultrasound 45 (2), 125-130



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