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New therapy of canine cutaneous mast cell tumors
Chemotherapy of mast cell tumors is currently done either with a prednisolone-cimetidine or lomustine-prednisolone-combination. In this article, another promising protocol especially fot localized mast cell tumors that are likely to recur owing to inadequate excision is described.

27 dogs with inadequately excised cutaneous mast cell tumors were treated with a combination from vinblastine and prednisolone.

20 dogs which were available for a follow-up one year later: 14 dogs showed no mast cell tumors, One dog showed local recurrence, four dogs had new tumors and one dog showed both.

There was no tumor-related mortality in all dogs. Although toxicity from the chemotherapy was generally mild, one dog dies of sepsis during treatment.

Source: Davies DR, Wyatt KM, Jardine JE et al (2004): `Vinblastine and Prednisolone as Adjunctive Therapy for Canine Cutaneous Mast Cell Tumors`. In: JAAHA Vol. 40 No. 2 pp 124-130


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SMALL ANIMAL PRACTICE

Punica granatum associated with hepatotoxicosis in cattlemembers
The ingestion of pomegranates was associated with the deaths of 9 of 35 young cattle; 8 were found dead without any prior clinical signs being noted and 1 animal was observed to be weak with pale‐pink mucous membranes. This case report describes also gross pathological and histopathological signs of the affected cattle and discusses the question which toxic principle was underlying in this case.

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  • Primary pulmonary histiocytic sarcoma in dogsmembers
  • Determining prognosis in canine sepsis members
  • Correlation of plasma and tear glucose, creatinine and urea nitrogen in catsmembers
  • Perineal hernias in dogs - always a bilateral problem?members
  • Pharmacokinetic of gabapentin in catsmembers
  • Follicular development of canine ovaries stimulated by eCG plus hCGmembers
  • Gastrointestinal effects following acupuncture in healthy dogsmembers
  • Bilateral repair of apparently unilateral perineal hernias in dogsmembers


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