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New therapy of canine cutaneous mast cell tumors
Chemotherapy of mast cell tumors is currently done either with a prednisolone-cimetidine or lomustine-prednisolone-combination. In this article, another promising protocol especially fot localized mast cell tumors that are likely to recur owing to inadequate excision is described.

27 dogs with inadequately excised cutaneous mast cell tumors were treated with a combination from vinblastine and prednisolone.

20 dogs which were available for a follow-up one year later: 14 dogs showed no mast cell tumors, One dog showed local recurrence, four dogs had new tumors and one dog showed both.

There was no tumor-related mortality in all dogs. Although toxicity from the chemotherapy was generally mild, one dog dies of sepsis during treatment.

Source: Davies DR, Wyatt KM, Jardine JE et al (2004): `Vinblastine and Prednisolone as Adjunctive Therapy for Canine Cutaneous Mast Cell Tumors`. In: JAAHA Vol. 40 No. 2 pp 124-130


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SMALL ANIMAL PRACTICE

Computed tomographic arthrography of the canine shoulder joint members
The aim of this retrospective, methods comparison study was to assess the diagnostic utility of computed tomographic arthrography in the assessment of various intraarticular shoulder pathologies in dogs in comparison with survey computed tomography (CT), using arthroscopic examination as the reference standard. Computed tomography, computed tomographic arthrography, and arthroscopic findings of 46 scapulohumeral joints of dogs with forelimb lameness were reviewed retrospectively.

  • Prognostic scoring system for dogs managed with hemodialysismembers
  • Sonography vs percutaneous palpation to identify targeted thoracolumbar intervertebral disc spacesmembers
  • Distribution of alveolar-interstitial syndrome in dogs and cats with respiratory distress members
  • Disorders of sex development in catsmembers
  • Core ocular surface microbiome in dogsmembers
  • ACVIM small animal consensus statement on safe use of cytotoxic chemotherapeutics members
  • MRI imaging of masticatory muscles in basset houndsmembers
  • Mucosal microbiota, gastrointestinal inflammation and small cell intestinal lymphoma in cats members
  • Efficacy of pentamidine analogue 6 in dogs with chronic atrial fibrillationmembers
  • Tick-borne relapsing fever in various speciesmembers
  • Canine hyperadrenocorticism associations with signalment, selected comorbidities and mortality members
  • Intracameral injection of epinephrine and 2% lidocaine in the eyes of healthy catsmembers


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