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New therapy of canine cutaneous mast cell tumors
Chemotherapy of mast cell tumors is currently done either with a prednisolone-cimetidine or lomustine-prednisolone-combination. In this article, another promising protocol especially fot localized mast cell tumors that are likely to recur owing to inadequate excision is described.

27 dogs with inadequately excised cutaneous mast cell tumors were treated with a combination from vinblastine and prednisolone.

20 dogs which were available for a follow-up one year later: 14 dogs showed no mast cell tumors, One dog showed local recurrence, four dogs had new tumors and one dog showed both.

There was no tumor-related mortality in all dogs. Although toxicity from the chemotherapy was generally mild, one dog dies of sepsis during treatment.

Source: Davies DR, Wyatt KM, Jardine JE et al (2004): `Vinblastine and Prednisolone as Adjunctive Therapy for Canine Cutaneous Mast Cell Tumors`. In: JAAHA Vol. 40 No. 2 pp 124-130


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SMALL ANIMAL PRACTICE

Reference intervals for blood parameters in Shetland Sheepdogsmembers
Several breeds have physiological peculiarities that induce variations in reference intervals (RIs) compared with the general canine population. Shetland sheepdogs (SSs) are reported to be more predisposed to different diseases (eg, hyperlipidemia, gallbladder mucocele, and hypothyroidism). Consequently, a breed‐specific approach is more often required. Thus, the aim of this study was to determine whether the RIs of the general canine population could be applied to that of SSs, and to generate breed‐specific RIs, where appropriate.

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