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Histopathology in primary glaucomas of Norwegian Elkhounds
Primary glaucomas in Norwegian Elkhounds are well-known. In this study, the histopatological changes of 31 eyes are described. This breed tends to develop a pectinate ligament dysplasia and/or trabecular meshwork dysplasia as well as a cystic degeneration of the iridociliary epithelial and/or peripheral retina.

A retrospective histopathologic study of primary glaucoma in the Norwegian Elkhound was undertaken with the study of 9 clinically normal eyes and 22 glaucomatous eyes. All glaucomatous eyes showed goniodysgenesis as manifested by pectinate ligament dysplasia and/or trabecular meshwork dysplasia. Cystic degeneration of the iridociliary epithelial and/or peripheral retina was present in a high percentage of both normotensive and glaucomatous eyes. Utilizing the scheme proposed by Smith et al. (Veterinary and Comparative Ophthalmology 1993; 3: 16-28) the morphology of this disease in the Norwegian Elkhound would be classified as an open-angle, closed-cleft glaucoma, with histopathologic alterations of the outflow pathway similar to that described in other breeds with primary glaucoma.

Source: Yoshie Oshima, Ellen Bjerkas, Robert L. Peiffer Jr (2004): Ocular histopathologic observations in Norwegian Elkhounds with primary open-angle, closed-cleft glaucoma. In: Veterinary OphthalmologyVolume 7 Issue 3 Page 185 - May 2004


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SMALL ANIMAL PRACTICE

Novel intratumoral therapy in canine transmissible venereal tumour
Canine transmissible venereal tumour (CTVT) is a naturally occurring contagious neoplasm of dogs located mainly on the external genitalia of both sexes. The course of vincristine chemotherapy, the most effective and practical therapy, is affected by the immune status of the host. The aim was to investigate recombinant human interferon alpha‐2a (rhIFNα‐2a) and vincristine for treatment of CTVT.

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