Home
http://www.virbac.fr/ http://www.boehringer-ingelheim.com/ http://www.novartis.com/ http://www.animalhealth.bayerhealthcare.com/
vetcontact
Vetrinär
Tiermedizin
  WELCOME  
vetcontact
Vetrinär
Tiermedizin
  Home  
  Login / Newsletter  
vetcontact
Vetrinär
Tiermedizin
  CONTACTS  
vetcontact
Vetrinär
Tiermedizin
  Classifieds  
  New Products  
  VetCompanies  
  VetSchools  
vetcontact
Vetrinär
Tiermedizin
  PROFESSION  
vetcontact
Vetrinär
Tiermedizin
  Edutainment  
  VetAgenda  
  Presentations  
  Posters  
  ESAVS  
  Specialisation  
vetcontact
Vetrinär
Tiermedizin
  INSIGHT  
vetcontact
Vetrinär
Tiermedizin
  Congress News  
  Picture Galleries  
vetcontact
Vetrinär
Tiermedizin
  PRODUCTS  
vetcontact
Vetrinär
Tiermedizin
  Bayer  
  Boehringer Ing.  
  Novartis  
  Virbac

 
  Simply book for less...  
    

Bovine    Equine    Small Animal Practice    Swine Practice    Articles    Vetjournal    
deutsch english español polski francais
Home / WELCOME / Archiv / Small Animal Practice /     
 
Low tidal volume ventilation in healthy beagle dogs
Is low tidal volume (VT) ventilation really associated with the development of respiratory acidosis and changes in lung function in healthy dogs? An important question! This randomized prospective experimental cross-over study on 5 healthy beagle dogs was performed to answer this question.


Dogs were anesthetized and randomly mechanically ventilated with VT of 6, 8, 10, 12, and 15 mL/kg while maintaining a constant minute volume.

Arterial blood gases and pulmonary mechanics were collected after 15 minutes of equilibration at each VT.

Repeated measures ANOVA was used to determine the effect of VT with a P-value of <0.05 considered significant, and a Pearson product moment was used to determine correlation between VT and pH and PaCO2.

VT had a significant effect on PaCO2 (P < 0.001) and on pH (P < 0.001) with lower VT being associated with higher PaCO2 and lower pH.

There was a strong correlation between VT and PaCO2 (r = –0.87) and VT and pH (r = 0.83). Increased airway pressures and pulmonary compliance were associated with increasing VT.

Conclusions: There is a predictable decrease in the pH, decrease in airway pressure, decrease in compliance, and increase in the PaCO2 associated with lower VT.

Low VT ventilation is well tolerated in healthy dogs; the role of low VT ventilation in dogs with acute lung injury/acute respiratory distress syndrome as well as the influence of positive end expiratory pressure requires further evaluation.


Source: Oura, T., Rozanski, E. A., Buckley, G. and Bedenice, D. (2012), Low tidal volume ventilation in healthy dogs. Journal of Veterinary Emergency and Critical Care, 22: 368–371. doi: 10.1111/j.1476-4431.2012.00749.x




Tell a friend   |   Print version   |   Send this article

SMALL ANIMAL PRACTICE

Patient-specific facemask to facilitate brain biopsymembers
The objective of this pilot study was to describe the application and first preliminary data of a novel MRI and CT compatible patient-specific facemask for stereotactic brain biopsy of intracranial lesions in dogs. Five client-owned dogs presenting for neurological deficits consistent with forebrain disease were included in the study. All dogs had MRI findings consistent with an intracranial lesion. But biopsies in this region are not easy to obtain. Does an individual face mask help?

  • RET-He to diagnose iron-deficient erythropoiesis in dogsmembers
  • Hypertriglyceridemia-Associated Proteinuria in Miniature Schnauzersmembers
  • Gastrointestinal dysmotility disorders in critically ill animalsmembers
  • Disorder of sex development in a cat with chromosome mosaicism members
  • Generalized discoid lupus erythematosus in dogs members
  • Epidermolysis bullosa acquisita in dogsmembers
  • Chiari-Like Malformation and Syringomyelia in American Brussels Griffon Dogsmembers
  • Efficacy and Potential Complications of Transjugular Liver Biopsymembers
  • Hypomagnesemia in Brachycephalic Dogsmembers
  • Comparison of two minimally invasive techniques for liver biopsy members
  • Topical aqueous sirolimus and the tear production members
  • JAK 1/2 inhibitor in the treatment of canine B-cell lymphomamembers


  • [ Home ] [ About ] [ Contact / Request ][ Disclaimer ]

    Copyright © 2001-2016 VetContact GmbH
    All rights reserved