Home
http://www.virbac.fr/ http://www.boehringer-ingelheim.com/ http://www.novartis.com/ http://www.animalhealth.bayerhealthcare.com/
vetcontact
Vetrinär
Tiermedizin
  WELCOME  
vetcontact
Vetrinär
Tiermedizin
  Privacy Policy  
  Home  
  Login / Newsletter  
vetcontact
Vetrinär
Tiermedizin
  CONTACTS  
vetcontact
Vetrinär
Tiermedizin
  Classifieds  
  New Products  
  VetCompanies  
  VetSchools  
vetcontact
Vetrinär
Tiermedizin
  PROFESSION  
vetcontact
Vetrinär
Tiermedizin
  Edutainment  
  VetAgenda  
  Presentations  
  Posters  
  ESAVS  
  Specialisation  
vetcontact
Vetrinär
Tiermedizin
  INSIGHT  
vetcontact
Vetrinär
Tiermedizin
  Congress News  
  Picture Galleries  
vetcontact
Vetrinär
Tiermedizin
  PRODUCTS  
vetcontact
Vetrinär
Tiermedizin
  Bayer  
  Boehringer Ing.  
  Novartis  
  Virbac

 
  Simply book for less...  
    

Bovine    Equine    Small Animal Practice    Swine Practice    Articles    Vetjournal    
deutsch english español polski francais
Home / WELCOME / Archiv / Small Animal Practice /     
 
Low tidal volume ventilation in healthy beagle dogs
Is low tidal volume (VT) ventilation really associated with the development of respiratory acidosis and changes in lung function in healthy dogs? An important question! This randomized prospective experimental cross-over study on 5 healthy beagle dogs was performed to answer this question.


Dogs were anesthetized and randomly mechanically ventilated with VT of 6, 8, 10, 12, and 15 mL/kg while maintaining a constant minute volume.

Arterial blood gases and pulmonary mechanics were collected after 15 minutes of equilibration at each VT.

Repeated measures ANOVA was used to determine the effect of VT with a P-value of <0.05 considered significant, and a Pearson product moment was used to determine correlation between VT and pH and PaCO2.

VT had a significant effect on PaCO2 (P < 0.001) and on pH (P < 0.001) with lower VT being associated with higher PaCO2 and lower pH.

There was a strong correlation between VT and PaCO2 (r = –0.87) and VT and pH (r = 0.83). Increased airway pressures and pulmonary compliance were associated with increasing VT.

Conclusions: There is a predictable decrease in the pH, decrease in airway pressure, decrease in compliance, and increase in the PaCO2 associated with lower VT.

Low VT ventilation is well tolerated in healthy dogs; the role of low VT ventilation in dogs with acute lung injury/acute respiratory distress syndrome as well as the influence of positive end expiratory pressure requires further evaluation.


Source: Oura, T., Rozanski, E. A., Buckley, G. and Bedenice, D. (2012), Low tidal volume ventilation in healthy dogs. Journal of Veterinary Emergency and Critical Care, 22: 368–371. doi: 10.1111/j.1476-4431.2012.00749.x




Tell a friend   |   Print version   |   Send this article

SMALL ANIMAL PRACTICE

Novel intratumoral therapy in canine transmissible venereal tumourmembers
Canine transmissible venereal tumour (CTVT) is a naturally occurring contagious neoplasm of dogs located mainly on the external genitalia of both sexes. The course of vincristine chemotherapy, the most effective and practical therapy, is affected by the immune status of the host. The aim was to investigate recombinant human interferon alpha‐2a (rhIFNα‐2a) and vincristine for treatment of CTVT.

  • Long-term outcome of dogs with primary immune-mediated thrombocytopeniamembers
  • Insulin treatment and IGF-I in cats with diabetes mellitusmembers
  • Color doppler ultrasound in neoplastic and non-neoplastic canine testicles members
  • Computed tomographic arthrography of the canine shoulder joint members
  • Prognostic scoring system for dogs managed with hemodialysismembers
  • Sonography vs percutaneous palpation to identify targeted thoracolumbar intervertebral disc spacesmembers
  • Distribution of alveolar-interstitial syndrome in dogs and cats with respiratory distress members
  • Disorders of sex development in catsmembers
  • Core ocular surface microbiome in dogsmembers
  • ACVIM small animal consensus statement on safe use of cytotoxic chemotherapeutics members
  • MRI imaging of masticatory muscles in basset houndsmembers
  • Mucosal microbiota, gastrointestinal inflammation and small cell intestinal lymphoma in cats members


  • [ Home ] [ About ] [ Contact / Request ] [ Privacy Policy ]

    Copyright © 2001-2018 VetContact GmbH
    All rights reserved