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Histoplasma-induced keratitis in a horse
This case report from Switzerland describes a unilateral keratitis in a horse which turned out to be caused by Histoplasma spp. Very unusual: the horse came from Germany, and Histoplasma spp. are thought to be non endemic in Europe...

A 5-year-old Holsteiner gelding from Germany was presented 2 months after a whitish discoloration of the left cornea was observed.

Cytologic examination revealed intra- and extracellular globular structures, up to 4 Āµm in size, consisting of a central spherical deeply basophilic body surrounded by an unstained halo.

The structures were morphologically consistent with Histoplasma spp. Infection with Histoplasma organisms is not endemic in Europe.

Topical use of fluconazole was successful in eliminating Histoplasma organisms within 10 days of initiation of treatment.


Source: Richter, Marianne, Hauser, Beat, Kaps, Simone & Spiess, Bernhard M. (2003): Keratitis due to Histoplasma spp. in a horse. In: Veterinary Ophthalmology 6 (2), 99-103.




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