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Carbimazole-associated hypersensitivity vasculitis in a cat with hyperthyroidism
Feline hyperthyroidism can be treated medically, surgically or with radioactive iodine. Carbimazole inhibits both triiodothyronine and thyroxine synthesis in the thyroid gland and reported side effects include mild eosinophilia, leucopenia and lymphocytosis, thrombocytopenia, elevated liver enzyme activities, gastrointestinal signs and skin abnormalities. Including vasculitis!

This case report describes a cat with carbimazole-associated apparent hypersensitivity vasculitis causing digital and tail necrosis, with multiple renal infarcts.

Withdrawal of carbimazole resulted in stable disease.


Source: Bowlt, K., Cattin, I. and Stewart, J. (2013), Carbimazole-associated hypersensitivity vasculitis in a cat. Journal of Small Animal Practice. doi: 10.1111/jsap.12154


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SMALL ANIMAL PRACTICE

Radiation Therapy for the Treatment of Sialocele in Dogs
Sialocele is a collection of saliva that has leaked from a damaged salivary gland or duct and is surrounded by granulation tissue. Surgery is the recognized first-line treatment. Recurrence rate after surgery is 5–14%. Salivary gland tissue is very sensitive to radiation therapy - so the aim of this new study was to characterize response rate and clinical course of dogs with sialocele treated with RT and to determine a starting dose for clinical use.

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