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Carbimazole-associated hypersensitivity vasculitis in a cat with hyperthyroidism
Feline hyperthyroidism can be treated medically, surgically or with radioactive iodine. Carbimazole inhibits both triiodothyronine and thyroxine synthesis in the thyroid gland and reported side effects include mild eosinophilia, leucopenia and lymphocytosis, thrombocytopenia, elevated liver enzyme activities, gastrointestinal signs and skin abnormalities. Including vasculitis!

This case report describes a cat with carbimazole-associated apparent hypersensitivity vasculitis causing digital and tail necrosis, with multiple renal infarcts.

Withdrawal of carbimazole resulted in stable disease.


Source: Bowlt, K., Cattin, I. and Stewart, J. (2013), Carbimazole-associated hypersensitivity vasculitis in a cat. Journal of Small Animal Practice. doi: 10.1111/jsap.12154


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SMALL ANIMAL PRACTICE

Shock index in identifying acute blood loss in healthy dogs
Does the shock index (SI) increase following blood donation and is it a more sensitive assessment of acute blood loss as heart rate (HR), blood pressure, and plasma Lactate? An interesting question! 20 client-owned clinically normal dogs were enrolled in this prospective study.

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