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Superficial necrolytic dermatitis in a cat: diagnostic findings (case report)
Superficial necrolytic dermatitis (“hepatocutaneous syndrome”) is diagnosed sometimes in older dogs and rarely in cats. It is characterized by both severe alterations of the liver (neoplasia, cirrhosis etc.) and by severe crusty skin lesions especially of the footpads and the mucocutaneous junctions in dogs. The skin lesions in this cat were completely different: it showed a pruritic alopecia.

This report describes the antemortem diagnosis and antemortem and postmortem findings of superficial necrolytic dermatitis with hepatopathy (i.e., hepatocutaneous syndrome) in a cat.

A 5-year-old Maine coon was evaluated because of a history of pruritic alopecia and liver enzyme elevations.

Abdominal ultrasonography revealed a reticular pattern to the hepatic parenchyma. Histopathological findings of the liver were nodular regeneration with bands of vacuolated hepatocytes and bile duct hyperplasia, characteristic of the hepatopathy frequently associated with superficial necrolytic dermatitis.

Skin histopathology revealed multifocal parakeratosis, midepidermal spongiosis, and basal cell hyperplasia consistent with superficial necrolytic dermatitis.


Source: Susan E. Kimmel, Wendy Christiansen, Kevin P. Byrne, (2003): Clinicopathological, Ultrasonographic, and Histopathological Findings of Superficial Necrolytic Dermatitis With Hepatopathy in a Cat . In: Journal of the American Animal Hospital Association 39:23-27 (2003)




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SMALL ANIMAL PRACTICE

Storage temperatures and container types and the urine protein : creatinine ratios
Preanalytic protein adsorption to polymer and glass container surfaces may decrease urine protein concentration measurements and urine protein: creatinine ratios (UPC). Does urine stored in PC or glass containers have lower UPC than urine stored in HP containers? The specific objective was to determine whether clinically relevant differences in UPC would be detected after storage in glass, PC, or HP containers using common storage times and temperatures. Twelve client‐owned dogs with proteinuria helped to answer these important questions.

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