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Superficial necrolytic dermatitis in a cat: diagnostic findings (case report)
Superficial necrolytic dermatitis (“hepatocutaneous syndrome”) is diagnosed sometimes in older dogs and rarely in cats. It is characterized by both severe alterations of the liver (neoplasia, cirrhosis etc.) and by severe crusty skin lesions especially of the footpads and the mucocutaneous junctions in dogs. The skin lesions in this cat were completely different: it showed a pruritic alopecia.

This report describes the antemortem diagnosis and antemortem and postmortem findings of superficial necrolytic dermatitis with hepatopathy (i.e., hepatocutaneous syndrome) in a cat.

A 5-year-old Maine coon was evaluated because of a history of pruritic alopecia and liver enzyme elevations.

Abdominal ultrasonography revealed a reticular pattern to the hepatic parenchyma. Histopathological findings of the liver were nodular regeneration with bands of vacuolated hepatocytes and bile duct hyperplasia, characteristic of the hepatopathy frequently associated with superficial necrolytic dermatitis.

Skin histopathology revealed multifocal parakeratosis, midepidermal spongiosis, and basal cell hyperplasia consistent with superficial necrolytic dermatitis.


Source: Susan E. Kimmel, Wendy Christiansen, Kevin P. Byrne, (2003): Clinicopathological, Ultrasonographic, and Histopathological Findings of Superficial Necrolytic Dermatitis With Hepatopathy in a Cat . In: Journal of the American Animal Hospital Association 39:23-27 (2003)




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SMALL ANIMAL PRACTICE

3 Serological Tests for Early Detection Of Leptospira-specific Antibodies
Leptospirosis in dogs is a disease of global importance. Early detection and appropriate therapeutic intervention are necessary to resolve infection and prevent zoonotic transmission. However, its diagnosis is hindered by nonspecific clinical signs and lack of rapid diagnostic tests of early infection. Recently, 2 rapid point-of-care tests (WITNESS Lepto [WITNESS Lepto, Zoetis LLC, Kalamazoo, MI, USA] and SNAP Lepto [SNAP Lepto, IDEXX Laboratories, Westbrook, ME, USA]) for detection of Leptospira-specific antibodies in canine sera were developed. This recently online published article compares three systems for early diagnosis.

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