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Novel therapy in canine granulomatous meningoencephalomyelitis
Granulomatous meningoencephalomyelitis (GME) is a fatal neurologic condition that causes brain lesions. It is also considered to be one of the most common neurologic problems in dogs. There are good news from Wisconsin: Cyclosporine therapy seems to be very promising in this condition.


A veterinary neurologist is having success in treating dogs with GME. Dr. Filippo Adamo of the University of Wisconsin-Madison School of Veterinary Medicine recently published in the Journal of the American Veterinary Medical Association that use of cyclosporine is showing promise.

`The drug is easy administer, and so far the only adverse effects have been hair discoloration and temporary reduction of white blood cells.`

The research shows that two of three dogs with GME became free of clinical signs in the preliminary study. Since then, more dogs with GME have been successfully treated with cyclosporine, the reports the University of Wisconsin.

Source: Researchers look at brain lesion treatment. In: DVM Newsmagazine Nov 29, 2004; www.dvmnewsmagazine.com/dvm/











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SMALL ANIMAL PRACTICE

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Canine transmissible venereal tumour (CTVT) is a naturally occurring contagious neoplasm of dogs located mainly on the external genitalia of both sexes. The course of vincristine chemotherapy, the most effective and practical therapy, is affected by the immune status of the host. The aim was to investigate recombinant human interferon alpha‐2a (rhIFNα‐2a) and vincristine for treatment of CTVT.

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