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Familial diabetes mellitus in Samoyed dogs
Diabetes mellitus is a common disease in middle aged and older dogs. Not too much is known about a genetic background. In this study, five closely related Samoyed dogs developed this disease suggesting that there might be a familial predisposition of diabetes mellitus at least in this breed.

Five adult Samoyed dogs from two unrelated litters were diagnosed with diabetes mellitus.

Two full-sibling male dogs (Family A) were raised in the same household.

The other three dogs, two female and one male, were also full siblings (Family B) raised in different households.

All five dogs developed polyuria and polydipsia and demonstrated fasting hyperglycemia and glucosuria.

Diabetes mellitus was diagnosed in all five dogs and responded to appropriate therapy with insulin.

The occurrence of insulin-dependent diabetes mellitus in multiple, closely related Samoyed dogs suggests a familial predisposition in this breed.


Source: Susan E. Kimmel, Cynthia R. Ward, Paula S. Henthorn, Rebecka S. Hess (2002): Familial Insulin-Dependent Diabetes Mellitus in Samoyed Dogs. In: Journal of the American Animal Hospital Association 38:235-238 (2002)



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SMALL ANIMAL PRACTICE

Reference intervals for blood parameters in Shetland Sheepdogsmembers
Several breeds have physiological peculiarities that induce variations in reference intervals (RIs) compared with the general canine population. Shetland sheepdogs (SSs) are reported to be more predisposed to different diseases (eg, hyperlipidemia, gallbladder mucocele, and hypothyroidism). Consequently, a breed‐specific approach is more often required. Thus, the aim of this study was to determine whether the RIs of the general canine population could be applied to that of SSs, and to generate breed‐specific RIs, where appropriate.

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