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Who knows Porphyromonas gulae, salivosa and denticani?
Up to 80 percent of the dogs develop peridontal diseases sometimes in their live, and these three kinds of bacteria are often involved in the disease process and often also damage internal organs. A new study gives also other very interesting insights in an old problem that probably requires new treatment strategies!

The Pfizer Animal Health study revealed one or more of the three most prevalent bacteria known to cause canine periodontal disease were found in 74 percent of dogs.

Porphyromonas gulae, Porphyromonas salivosa and Porphyromonas denticani bacteria have been linked to diseases of the heart, kidney and lungs.

Several members of the genus Bacteroides were reclassified as members of the newly named Porphyromonas genus because scientists discovered the bacteria had a distinctive DNA sequence.

Their prevalence has prompted Pfizer to plan a study to monitor long-term effects of the three bacteria on bone loss related to periodontal disease. Pfizer researchers are hopeful their research will lead to new ways to prevent periodontal disease in dogs.

`Many dog owners don`t check their dog`s teeth and gums until they notice bad breath or their veterinarian identifies periodontal disease,` says Dr. David Haworth, manager, Veterinary Medicine Research & Development, Biologicals Clinical Development, Pfizer Animal Health. `Yet, maintaining healthy teeth is critical to keeping a dog healthy. We have finally been able to identify the three most common bacterial causes of canine oral health problems. That is a strong step toward helping veterinarians combat the problem.`


Source: DVM Newsmagazine Jan 1, 2005 ; www.dvmnewsmagazine.com/dvm/



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SMALL ANIMAL PRACTICE

Variability of SDMA in apparently healthy dogsmembers
Symmetric dimethylarginine (SDMA) is a screening tool for early kidney dysfunction and monitoring treatment in cases of chronic kidney disease (CKD). There are no current studies describing the suitability of this test for use with published population‐based reference intervals. The objectives of this study were to determine the components of biological variability, the index of individuality (IOI), the critical difference between sequential measurements (CD) and the number of measurements required to assess the homeostatic set point (HSP), for both SDMA and serum creatinine (sCr), in apparently healthy dogs.

  • Bioavailability of suppository acetaminophen in dogsmembers
  • Computed tomographic lymphography for lymph node staging in dogs with malignant tumors members
  • Characterization of ocular melanosis-affected canine melanocytesmembers
  • Nasopharyngeal sialoceles in brachycephalic dogsmembers
  • Enterococcus faecium SF68 on serum cobalamin and folate concentrationsmembers
  • Gastrointestinal eosinophilic sclerosing fibroplasia limited to the mesentery in a catmembers
  • Ion acid-base disturbances and associated mortality in dogsmembers
  • First description of ultrasonic bone curette in canine otic surgerymembers
  • Staining hair samples with a modified Wright-Giemsa stain to diagnose feline dermatophytosismembers
  • Oral extended release hydrocodone as analgesia after TPLOmembers
  • 25OH vitamin D3 serum concentration in dogs with acute polyradiculoneuritismembers
  • Type 1 immune mediated polyarthritis in dogs and temporal relationship to vaccination members


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