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Reintroduction of the recalled heartworm preventive Proheart 6?
Some months ago, the producer of the moxidectin-containing Proheart 6, Fort Dodge Animal Health, recalled the drug voluntarily due to an increase in adverse-reaction reporting. Now the company vows to work with the FDA to get it back on the market. The Veterinary Medicine Advisory Committee is split...

An independent review panel on Proheart 6 was split down the middle when asked to make a decision on questions of safety for the industry`s only injectable heartworm medication.

The 15-member panel, organized through the FDA`s Veterinary Medicine Advisory Committee (VMAC), was charged with making a recommendation to FDA on the fate of Proheart 6.

Dr. Lawrence Glickman, professor of epidemiology and public health and head of the clinical epidemiology section of Purdue University`s School of Veterinary Medicine, presented data reviewing almost 7 million canine visits at more than 400 Banfield hospitals.

These data showed a safety profile similar to two other heartworm preventives on the market. He recommended its reintroduction to the market.

About half of committee members cited a need for further research to more clearly understand the seeming disparity between serious adverse drug events attributed to moxidectin before its recall and the most recent survey. The other half of VMAC`s committee was satisfied with the safety data presented.

FDA plans to review the new information before a final decision is made on the fate of the product. No timeline for a decision was set.

Source: www.dvmnewsmagazine.com/dvm/






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SMALL ANIMAL PRACTICE

Electroretinography as a prognostic indicator after retinal reattachment surgery
Retinal detachment is one of the ophthalmological emergencies, and even if the diagnosis is made early and a reattachment surgery is performed immediately many dogs do not regain postoperative vision. This 18‐month prospective study recorded signalment, duration, cause, and extent of retinal detachment and pre‐operative vision status. Rod and mixed rod‐cone ERG responses were recorded prior to RRS. Referring veterinary ophthalmologists assessed vision 2 months postoperatively to determine whether pre‐operative electroretinography (ERG) predicts postoperative vision in dogs undergoing retinal reattachment surgery (RRS).

  • Computed tomographic lymphography for lymph node staging in dogs with malignant tumors members
  • Characterization of ocular melanosis-affected canine melanocytesmembers
  • Nasopharyngeal sialoceles in brachycephalic dogsmembers
  • Enterococcus faecium SF68 on serum cobalamin and folate concentrationsmembers
  • Gastrointestinal eosinophilic sclerosing fibroplasia limited to the mesentery in a catmembers
  • Ion acid-base disturbances and associated mortality in dogsmembers
  • First description of ultrasonic bone curette in canine otic surgerymembers
  • Staining hair samples with a modified Wright-Giemsa stain to diagnose feline dermatophytosismembers
  • Oral extended release hydrocodone as analgesia after TPLOmembers
  • 25OH vitamin D3 serum concentration in dogs with acute polyradiculoneuritismembers
  • Type 1 immune mediated polyarthritis in dogs and temporal relationship to vaccination members
  • Phosphorus and protein supply before diagnosis of chronic kidney disease members


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