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Spontaneous chronic defects of the corneal epithelium in dogs
This problem is well-known in certain breeds, especially in brachycephalic dogs like pugs, boxers and so on. But any breed can be affected, this is one of the surprising results of this brandnew study. Which therapy is the best?

Spontaneous chronic corneal epithelial defects (SCCEDs) in dogs are typically found in middle-aged dogs of all breeds.

These epithelial defects may be present for weeks to months, particularly if left untreated or if treated inappropriately.

Typical histopathological findings include loss of the corneal epithelial basement membrane and formation of a superficial, acellular, hyalinized zone in the stroma.

Together, these histological abnormalities lead to delayed wound healing and poor epithelial adhesion.

Epithelial debridement, anterior stromal puncture, grid keratotomy, and superficial keratectomy are the most common treatment options applied to the defects.

Procedures that address the stromal changes present generally have a higher success rate than epithelial debridement alone.


Source: Ellison Bentley (2005): Spontaneous Chronic Corneal Epithelial Defects in Dogs: A Review. In: Journal of the American Animal Hospital Association 41:158-165 (2005)




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SMALL ANIMAL PRACTICE

Novel intratumoral therapy in canine transmissible venereal tumour
Canine transmissible venereal tumour (CTVT) is a naturally occurring contagious neoplasm of dogs located mainly on the external genitalia of both sexes. The course of vincristine chemotherapy, the most effective and practical therapy, is affected by the immune status of the host. The aim was to investigate recombinant human interferon alpha‐2a (rhIFNα‐2a) and vincristine for treatment of CTVT.

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