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Incidence and breed-related risk factors of gastric dilatation/volvulus
It is well known that large and giant breeds especially those with deep chests are prone to develop dilatation-volvulus (GDV). This large study (nearly 2000 dogs) evaluated incidence of and breed-related risk factors for this life-threatening disease among 11 dog breeds and got very interesting results.

1,914 dogs of the following breeds were included in this study: Akita, Bloodhound, Collie, Great Dane, Irish Setter, Irish Wolfhound, Newfoundland, Rottweiler, Saint Bernard, Standard Poodle, and Weimaraner which was performed as a prospective cohort study.

Owners of dogs that did not have a history of GDV were recruited at dog shows, and the dog`s length and height and depth and width of the thorax and abdomen were measured.

Information concerning the dogs` medical history, genetic background, personality, and diet was obtained from owners, and owners were contacted by mail and telephone at approximately 1-year intervals to determine whether dogs had developed GDV or died.

Incidence of GDV based on the number of dog-years at risk was calculated for each breed, and breed-related risk factors were identified.

RESULTS AND CLINICAL RELEVANCE: Incidence of GDV for the 7 large (23 to 45 kg [50 to 99 lb]) and 4 giant (> 45 kg [> 99 lb]) breeds was 23 and 26 cases/1,000 dog-years at risk, respectively.

Of the 105 dogs that developed GDV, 30 (28.6%) died. Incidence of GDV increased with increasing age.

Cumulative incidence of GDV was 5.7% for all breeds.

The only breed-specific characteristic significantly associated with a decreased incidence of GDV was an owner-perceived personality trait of happiness.


Source: Glickman LT, Glickman NW, Schellenberg DB, Raghavan M, Lee TL (2000): Incidence of and breed-related risk factors for gastric dilatation-volvulus in dogs. In: J Am Vet Med Assoc. 2000 Jan 1;216(1):40-5.




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SMALL ANIMAL PRACTICE

3 Serological Tests for Early Detection Of Leptospira-specific Antibodies
Leptospirosis in dogs is a disease of global importance. Early detection and appropriate therapeutic intervention are necessary to resolve infection and prevent zoonotic transmission. However, its diagnosis is hindered by nonspecific clinical signs and lack of rapid diagnostic tests of early infection. Recently, 2 rapid point-of-care tests (WITNESS Lepto [WITNESS Lepto, Zoetis LLC, Kalamazoo, MI, USA] and SNAP Lepto [SNAP Lepto, IDEXX Laboratories, Westbrook, ME, USA]) for detection of Leptospira-specific antibodies in canine sera were developed. This recently online published article compares three systems for early diagnosis.

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