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Itraconazole pulse therapy in dogs with malassezia dermatitis
Azoles are proven to be very effective in the therapy of malassezia dermatitis in dogs. The `classic` azole for this indication is ketoconazole which is given one to three times a day. Is itraconazole pulse therapy a good alternative as it is in feline and human dermatophytosis? An interesting study presented at the 20th Annual Congess of the European Society of Veterinary Dermatology in Chalkidiki!

20 dogs with a proven pruritic malassezia dermatitis were included in the study.

Group A was treated with ketoconazole 5-10 mg/kg daily, group B was treated with itraconazole 5 mg/kg 2 times a week.

After 3 weeks, no statistical differences between the two groups regarding pruritus, clinical signs (evaluated by CADESI score) and number of Malassezia yeasts on cytological preparations were found.

Thus, itraconazole pulse therapy was considered to be as effective as daily ketoconazole in the therapy of canine malassezia dermatitis.

Source: Bensignor, E. (2005): Efficacy of itraconazole as a pulse therapy in canine malassezia dermatitis. In: Proceedings of the 20th Annual Congress of the ESVD-ECVD Chalkidiki, Greece, 8-10 September, 200f, p. 192


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SMALL ANIMAL PRACTICE

Reference intervals for blood parameters in Shetland Sheepdogsmembers
Several breeds have physiological peculiarities that induce variations in reference intervals (RIs) compared with the general canine population. Shetland sheepdogs (SSs) are reported to be more predisposed to different diseases (eg, hyperlipidemia, gallbladder mucocele, and hypothyroidism). Consequently, a breed‐specific approach is more often required. Thus, the aim of this study was to determine whether the RIs of the general canine population could be applied to that of SSs, and to generate breed‐specific RIs, where appropriate.

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