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Feline mucinous cholangiocarcinoma (case report)
A marked peritoneal effusion is not always associated with heart failure or viral diseases like FIP, it can also be due to a rare neoplasia like cholangiocarcinoma. A very interesting case report illustrating the difficulties to get to the diagnosis of this rare neoplasia!

Mucinous cholangiocarcinoma was diagnosed in a 14-year-old, castrated male, domestic shorthaired cat with marked peritoneal effusion. Cytological confirmation of malignancy by fluid analysis and fine-needle, ultrasound-guided aspiration of the liver was followed by histological examination of tissue samples obtained at surgery and necropsy. No observed response followed chemotherapy with doxorubicin and carboplatin. Electron microscopy and immunohistochemistry helped to further characterize this unusual tumor.


Source: Terry M. Jacobs, Paul W. Snyder (2007): Mucinous Cholangiocarcinoma in a Cat. In: Journal of the American Animal Hospital Association 43:168-172 (2007)




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SMALL ANIMAL PRACTICE

Reference intervals for blood parameters in Shetland Sheepdogsmembers
Several breeds have physiological peculiarities that induce variations in reference intervals (RIs) compared with the general canine population. Shetland sheepdogs (SSs) are reported to be more predisposed to different diseases (eg, hyperlipidemia, gallbladder mucocele, and hypothyroidism). Consequently, a breedâ€specific approach is more often required. Thus, the aim of this study was to determine whether the RIs of the general canine population could be applied to that of SSs, and to generate breedâ€specific RIs, where appropriate.

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