The purpose of this study was to evaluate the usefulness of cytologdiagnostic accuracy of these methods.ic investigation of prostatic disease using US-FNA and other methods in comparison with histopathologic diagnosis.
METHODS: Cytologic and histopathologic specimens of prostate or paraprostatic tissue from 25 adult dogs were retrospectively evaluated.
Cytologic samples were obtained by US-FNA, prostatic massage, or direct impression smears or aspirates of tissue at surgery.
Histopathologic sections were obtained from tissue collected by biopsy or at necropsy.
RESULTS: Cytologic diagnoses were categorized as nondiagnostic (n = 2); cyst (n = 1); squamous metaplasia (n = 2); inflammation (n = 4); benign prostatic hyperplasia (BPH; n = 5); inflammation and BPH (n = 3); inflammation, BPH, and neoplasia (n = 1); inflammation and neoplasia (n = 3); and neoplasia (n = 4).
Cytologic diagnoses agreed with final histologic diagnoses in 20 of the 25 cases (80%).
Of those samples collected by US-FNA, 75% were concordant. Four samples obtained by US-FNA and 1 sample obtained by prostatic massage and wash had discordant results.
CONCLUSIONS: The results of this study suggest strong agreement between cytologic and histopathologic diagnoses for prostatic conditions. Discordance in results obtained by US-FNA usually was the result of the pathologic process rather than a failure to obtain an appropriate sample.
Source: Powe JR, Canfield PJ, Martin PA. (2004): Evaluation of the cytologic diagnosis of canine prostatic disorders. In: Vet Clin Pathol. 2004;33(3):150-4.
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