Sections of 14 skin biopsies of cats with plasmacytic pododermatitis and a clinical follow-up of 1236 months were stained with a polyclonal anti-Mycobacterium bovis (Bacille Calmette-Guerin = BCG) antibody cross-reactive to a broad spectrum of fungi and bacteria.
All sections were negative for organisms within the actual footpad tissue with the anti-BCG antibody stains.
Polymerase chain reaction (PCR) assays that amplify the DNA of Bartonella spp., Ehrlichia spp., Anaplasma phagocytophilum, Chlamydophila felis, Mycoplasma spp., Toxoplasma gondii, and feline herpesvirus 1 (FHV-1) were applied to tissue digests. DNA of those pathogens assessed was not amplified from tissue.
Source: S. V. Bettenay, M. R. Lappin and R. S. Mueller (2007): An Immunohistochemical and Polymerase Chain Reaction Evaluation of Feline Plasmacytic Pododermatitis. In: Vet Pathol 44:80-83 (2007)
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