INSULIN-LIKE GROWTH FACTOR I CONCENTRATION IN DOGS WITH LIVER DISEASES
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In men, liver diseases are known to influence the serum concentration of insulin-like growth factor I (IGF-I). Is the same true for dogs? This recently published study from Germany compares serum IGF-I concentrations of dogs with primary liver diseases, healthy dogs and dogs with non-hepatic diseases.
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For this purpose, IGF-I serum concentrations were measured (DSL-5600 kit) in 36 dogs with various liver diseases and compared with 22 healthy controls and 20 dogs with non-hepatic diseases.
The results showed that dogs with liver diseases had significantly lower IGF-I serum concentrations (P < 0.001) than clinical healthy dogs or dogs with non-hepatic diseases.
But the results also indicate that the aetiology of liver disease has no influence on IGF-I serum concentration.
Source: S. Neumann, H. Welling, S. Thuere (2007): Insulin-like Growth Factor I Concentration in Dogs with Inflammatory and Neoplastic Liver Diseases. In: Journal of Veterinary Medicine Series A 54 (10), 612617.
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