Ten client-owned cats with FISS were included.
A fiducial marker detectable on CTA and MRI was sutured to the skin over the FISS as a standard reference point.
All cats received MRI and CTA of the FISS, immediately followed by wide surgical excision.
Targeted microscopic evaluation was performed on tissue with imaging-identified lesions and on the surgical margins.
A total of 87 imaging-identified peritumoral lesions were examined microscopically (median 4 per cat, range 3–9) with 17/87 (20%) categorized as neoplastic, 51/87 (59%) as nonneoplastic, and 19/87 (22%) as equivocal.
In 25 instances, peritumoral lesions were seen on both imaging modalities at the same location.
Unique imaging characteristics were seen in 5/17 neoplastic peritumoral lesions (4 cats; all different lesions; 1 CTA, 4 MRI).
The CTA and MRI appearances of the remaining 12/17 neoplastic lesions were nonspecific, being observed across more than 1 microscopic category.
CTA and MRI identified a similar number of peritumoral lesions.
The extensive overlap between imaging features of neoplastic and nonneoplastic lesions precludes definitive identification of neoplastic peritumoral FISS lesions using CTA or MRI.
Source: Nemanic, S., Milovancev, M., Terry, J. L., Stieger-Vanegas, S. M. and Löhr, C. V. (2016), Microscopic Evaluation of Peritumoral Lesions of Feline Injection Site Sarcomas Identified by Magnetic Resonance Imaging and Computed Tomography. Veterinary Surgery. doi: 10.1111/vsu.12448
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