This prospective cohort study enrolled 24 client-owned dogs with acute kidney injury.
Cardiac disorders were evaluated with thoracic radiographs, echocardiography, 24-hour Holter monitoring and cardiac troponin I concentrations within 2 days of admission and 7 to 10 days later.
Most dogs were diagnosed with leptospirosis (n=18, 75%) and presented with moderate-to-severe acute kidney injury, International Renal Interest Society grades III to V.
Dogs with ê100 ventricular premature complexes per 24 hour in the first examination (n=8) had significantly higher initial cTnI concentrations (P=0·007) compared to dogs with fewer than 100.
In receiver operating characteristic curve analysis, the number of ventricular premature complexes was predictive of outcome (AUC 0·83, P<0·001).
Acute kidney injury seems to be associated with cardiac injury and arrhythmias in dogs.
The data do not indicate a cardiac cause of poor outcome in dogs with increased number of ventricular premature complexes but the association may reflect the severity of disease.
Source: Keller, S. P., Kovacevic, A., Howard, J., Schweighauser, A. and Francey, T. (2016), Evidence of cardiac injury and arrhythmias in dogs with acute kidney injury. Journal of Small Animal Practice. doi: 10.1111/jsap.12495
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