TJLBs were procured through the right jugular vein.
After biopsy, intravenous contrast and gross inspection were used to assess the biopsy site.
Minor and major complications were recorded.
NLBs and SLBs were then obtained.
Histopathology was performed, and TJLB and NLB were compared. Pathologic process and autolysis were assessed in all samples.
All TJLBs yielded liver tissue.
The proportion of minor complications was 12/25 (48%), and major complications 16/25 (64%); 13/16 (81%) of the major complications were liver capsule perforation.
In 21/25 (84%), the histopathology in the SLB was reflected in the TJLBs.
For cases with minimal autolysis, median number of CPTs in TJLBs was 7.5, compared with 4 in NLBs (P = .018).
Median length of TJLB specimen was 28 mm compared to 22 mm in NLBs (P = .007).
Fragmentation rate was median of 1.25 for TJLB compared to 1.50 in NLBs (P = .11).
TJLB is technically feasible and achieves comparable results to NLB and SLB. The number of complications, in particular liver capsule perforation, was greater than expected. Further studies are indicated before clinical use is recommended.
Source: Levien, A.S., Weisse, C., Donovan, T.A. and Berent, A.C. (2014), Assessment of the Efficacy and Potential Complications of Transjugular Liver Biopsy in Canine Cadavers. Journal of Veterinary Internal Medicine, 28: 338–345. doi: 10.1111/jvim.12305
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