Four hundred sixty-two cats with untreated hyperthyroidism were enrolled, 117 of which were reevaluated after treatment.
The study design was a prospective cross-sectional and before–after studies. Untreated hyperthyroid cats had body composition evaluated (body weight, BCS, and MCS). A subset of these cats were reevaluated 3–12 months after treatment when euthyroid.
Pretreatment body weight (median, 4.36 kg; IQR, 3.5 to 5.2 kg) was lower than premorbid weight (5.45 kg; IQR, 4.6 to 6.4 kg, P < .0001) recorded 1–2 years before diagnosis.
154 (35.3%) cats were thin or emaciated; 357 (77.3%) had loss of muscle mass.
Cats showed increases in body weight (median, 4.1 kg to 5.0 kg), BCS (median, 3/5 to 3.5/5), and MCS (2/3 to 3/3) after treatment (P < .001), but mild-to-moderate muscle wasting persisted in 45% of treated cats.
Most hyperthyroid cats lose body weight but maintain an ideal or overweight BCS, with only a third being underweight.
As in human hyperthyroid patients, this weight loss is associated with muscle wasting, which affects >75% of hyperthyroid cats.
Successful treatment leads to weight gain and increase of BCS in most cats, but almost half fail to regain normal muscle mass.
Source: Peterson, M.E., Castellano, C.A. and Rishniw, M. (2016), Evaluation of Body Weight, Body Condition, and Muscle Condition in Cats with Hyperthyroidism. Journal of Veterinary Internal Medicine, 30: 1780–1789. doi: 10.1111/jvim.14591
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