34 adult client-owned dogs were inluded in this study.
Dogs undergoing elective or emergency orthopedic surgery had whole blood collected before (T0), at 24 hours (T1), and 1 week (T2) after surgery.
Whole blood from each dog was collected by jugular venipuncture using a 20-Ga needle and minimum venous stasis.
The blood was placed into tubes containing 3.8% trisodium citrate (1 part citrate: 9 parts blood) and rested at 37°C.
Coagulation was evaluated by means of thromboelastometry using the in-TEM, ex-TEM, and fib-TEM assays.
Statistically significant increases (P < 0.05) in maximum clot firmness (MCF) from T0 to T1 in the in-TEM and fib-TEM profiles (both P = 0.0001), from T0 to T2 in the in-TEM, ex-TEM, and fib-TEM profiles (P = 0.012, P = 0.037, and P = 0.0001, respectively), and from T1 to T2 in the fib-TEM profile (P = 0.039) were noted.
The α angle increased from T0 to T2 in the in-TEM and ex-TEM profiles (P = 0.019 and P = 0.036, respectively).
All results were, however, within the institutional reference ranges.
In this study, unlike the hypercoagulability observed in human orthopedic patients, a hypercoagulable state as measured by thromboelastometry did not develop in dogs following orthopedic surgery.
Source: Bruno, B., Maurella, C., Falco, S., Tarducci, A., Zanatta, R., Gianella, P., D`Angelo, A., Piras, L., Di Bella, A. and Borrelli, A. (2015), Assessment of coagulation utilizing thromboelastometry in dogs undergoing orthopedic surgery. Journal of Veterinary Emergency and Critical Care. doi: 10.1111/vec.12300
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