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Topical eprinomectin in the treatment of Psoroptes cuniculi
Macrocyclic lactones are thought to be the most effective weapons against Psoroptes cuniculi and related mites. Various protocols for the use of ivermectin, doramectin etc. exist. Is the eprinomectin spot-on for cattle which is so easy to administer equally effective? It does not seem so...

Six rabbits naturally infested with Psoroptes cuniculi were treated topically on the skin at the base of the neck with 0.5 mg per kg of 0.5% pour-on eprinomectin for cattle, twice at 14-day intervals.

Efficacy of the drug was based on the disappearance of clinical signs and the absence of live mites for a period of 6 weeks.

Clinical improvement was seen within 3 days of the first application; however, complete recovery of clinical signs and elimination of mites in 5/6 rabbits did not occur until the end of the study.

No adverse reactions attributable to eprinomectin treatment were observed during the observation period.

Results of this trial indicated that eprinomectin was partially effective in the treatment of psoroptic mange in rabbits.


Source: ULUTAS, BULENT, VOYVODA, HUSEYIN, BAYRAMLI, GOKSEL & KARAGENC, TULIN (2005): Efficacy of topical administration of eprinomectin for treatment of ear mite infestation in six rabbits. In: Veterinary Dermatology 16 (5), 334-337.





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SMALL ANIMAL PRACTICE

Novel intratumoral therapy in canine transmissible venereal tumour
Canine transmissible venereal tumour (CTVT) is a naturally occurring contagious neoplasm of dogs located mainly on the external genitalia of both sexes. The course of vincristine chemotherapy, the most effective and practical therapy, is affected by the immune status of the host. The aim was to investigate recombinant human interferon alpha‐2a (rhIFNα‐2a) and vincristine for treatment of CTVT.

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