Home
http://www.virbac.fr/ http://www.boehringer-ingelheim.com/ http://www.novartis.com/ http://www.animalhealth.bayerhealthcare.com/
vetcontact
Vetrinär
Tiermedizin
  WELCOME  
vetcontact
Vetrinär
Tiermedizin
  Home  
  Login / Newsletter  
vetcontact
Vetrinär
Tiermedizin
  CONTACTS  
vetcontact
Vetrinär
Tiermedizin
  Classifieds  
  New Products  
  VetCompanies  
  VetSchools  
vetcontact
Vetrinär
Tiermedizin
  PROFESSION  
vetcontact
Vetrinär
Tiermedizin
  Edutainment  
  VetAgenda  
  Presentations  
  Posters  
  ESAVS  
  Specialisation  
vetcontact
Vetrinär
Tiermedizin
  INSIGHT  
vetcontact
Vetrinär
Tiermedizin
  Congress News  
  Picture Galleries  
vetcontact
Vetrinär
Tiermedizin
  PRODUCTS  
vetcontact
Vetrinär
Tiermedizin
  Bayer  
  Boehringer Ing.  
  Novartis  
  Virbac

 
  Simply book for less...  
    

Bovine    Equine    Small Animal Practice    Swine Practice    Articles    Vetjournal    
deutsch english español polski francais
Home / WELCOME / Archiv / Equine /     
 
Two different inactivated vaccines for prevention of Rhodococcus equi pneumonia in foals
Not too common but very dramatically: Rhodococcus equi pneumonia in young foals. This interesting study from Hungary evaluates the efficacy of two different vaccines applied to the pregnant mares. One of the results: It seems more promising to vaccinate the foals instead of the mothers.

Two different, inactivated, aluminium salt adsorbed vaccines, one containing a R. equi strain (serotype 1, 10(9) CFU/ml and equine herpesvirus 2 (EHV-2) (1.5 x 10(7) PFU/ml) and another containing R. equi only were used on three studfarms to determine whether the disease can be prevented by vaccination of both pregnant mares and their foals.

Pregnant mares received two 3 ml doses of vaccine intramuscularly 6 and 2 weeks before parturition and their foals were vaccinated on two or three occasions at 3, 5 or 7 weeks of age.

The efficacy of the vaccines was evaluated on the basis of the clinical signs, serological response (indirect haemagglutination and virus neutralisation tests) and culture of R. equi from sick or dead foals.

On studs A and B where the bivalent vaccine was used, 24 and 14 foals were born respectively to the vaccinated mares but no clinical case or death occurred due to R. equi pneumonia, while out of the 10 nonvaccinated control foals (stud B) two succumbed to R. equi pneumonia and 4 other foals had to be treated with antibiotics because of fever, coughing and dyspnea.

In stud C, where the vaccine containing R. equi strain alone was used, all 15 vaccinated foals remained healthy but one of the 11 control foals died of suppurative R. equi pneumonia and one foal had to be treated due to R. equi pneumonia.

R. equi strains (serotype 1) were isolated from the lungs of all dead foals.

The serological response was very weak to both R. equi and the EHV-2 strain. Antibody titres in the colostrum of the vaccinated mares against R. equi (in studs A and B, geometric mean 3.79 +/- 1.63 and 4.14 +/- 1.46, respectively) were practically not higher than titres in the controls (in stud B geometric mean 2.12 +/- 1.96).

More antibody was present in the colostrum samples against EHV-2 (geometric mean 6.1 + 1.4 compared to 2.5 +/- 1.2).

In all foals antibody levels were hardly detectable against both R. equi and EHV-2 until five weeks of age.

From the fifth week, antibody levels gradually increased and by the ninth week their reached a titre of 5.5 +/- 1.8 (2.7 +/- 1.2 in the control foals) against R. equi and 5.2 +/- 1.4 against EHV-2.

The favorable clinical results and the low antibody titres in the sera of the vaccinated foals during the first week of life suggest that protection probably was due to repeated vaccination of young foals rather than to vaccination of mares.

Source: Varga J, Fodor L, Rusvai M, Soos I, Makrai L. (1997): Prevention of Rhodococcus equi pneumonia of foals using two different inactivated vaccines. In: Vet Microbiol. 1997 Jun 16;56(3-4):205-12.



Tell a friend   |   Print version   |   Send this article

EQUINE

CT description of equine oromaxillary sinus and oronasal fistulaemembers
Oronasal and oromaxillary sinus fistulae are well‐documented complications following removal or loss of a maxillary cheek tooth. Diagnosis is currently based on a combination of oral examination, videoendoscopy, radiography, and computed tomography (CT). The objective of this retrospective, case series study was to describe the CT characteristics of confirmed oronasal and oromaxillary sinus fistulae in a group of horses.

  • Insulin and the structural integrity of equine digital lamellaemembers
  • Exercise-induced pulmonary haemorrhage in Thoroughbred racehorsesmembers
  • Specific bioactive collagen peptides (PETAGILE®) in horses with osteoarthritismembers
  • Epidural anaesthesia in horses with perineal and tail melanomasmembers
  • Unexpected cause of haematuria in an Egyptian Arabian stallionmembers
  • First description of hypersplenism in an old miniature ponymembers
  • Endocrinopathies associated with severe hypertriglyceridaemia in horses and poniesmembers
  • Clinical effect of corticosteroids in horses with asthmamembers
  • Severe complications of cheek tooth extraction in a ponymembers
  • Septic keratitis - associated bacteria and antibiotic susceptibilitymembers
  • Traumatic coccygeal luxation and distal amputation of the tail of a horsemembers
  • Head computed tomography in equine practicemembers


  • [ Home ] [ About ] [ Contact / Request ][ Disclaimer ]

    Copyright © 2001-2016 VetContact GmbH
    All rights reserved