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Thyroid carcinoma in dogs - is surgical resection sufficient?
An important question - thyroid carcinomas in dogs are not too common and can be extremly difficult to resect. So it is important to know before planning surgery which prognosis and which concurrent therapy should be recommended to the owner.

Of 82 dogs with thyroid carcinoma seen between January 1981 and October 1989, 20 had freely movable tumors without evidence of metastasis and were treated with surgical excision alone.

Uncensored mean and median survival times for these 20 dogs were both 20.5 months.

Kaplan-Meier survival analysis, which censors for nontumor-related deaths and dogs lost to follow-up, indicated that median survival time was greater than 36 months.

Seven dogs died of tumor-related causes: 2 died because of metastasis or local recurrence of the tumor, 5 died of treatment-related complications (eg, laryngeal paralysis, hypocalcemia, tracheostomy complications).
Eight dogs died of unrelated causes; 1 dog was lost to follow-up at 26 months after surgery; 3 dogs were alive 19, 24, and 26 months after surgery.
Cause of death could not be determined in the remaining dog.

Long-term survival is possible following surgical removal of mobile thyroid carcinomas in dogs.


Source: Klein MK, et al (1995): Treatment of thyroid carcinoma in dogs by surgical resection alone: 20 cases (1981-1989). In: J Am Vet Med Assoc. 1995 Apr 1;206(7):1007-9.



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SMALL ANIMAL PRACTICE

Microbiota of traumatic, open fracture wounds and the mechanism of injury
Open fractures are characterized by disruption of the skin and soft tissue, which allows for microbial contamination and colonization. Preventing infection‐related complications of open fractures and other acute wounds remains an evolving challenge due to an incomplete understanding of how microbial colonization and contamination influence healing and outcomes. Culture‐independent molecular methods are now widely used to study human‐associated microbial communities without introducing culture biases. This recently online published study describes the fascinating association between the mechanism of injury and the microbiota of the wounds.

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