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Changes in bone and soft tissue after surgery of cranial cruciate ligament rupture
A standard surgery especially in large and giant dogs: repair of the rupture of the cranial cruciate ligament. But who knows what happens with the bone and soft tissue after surgery? A very interesting recently published study from the University of Tennessee.

Following cranial cruciate ligament transection and extracapsular stabilization, dual-energy X-ray absorptiometry was used to analyze bone mineral content and lean tissue mass in the surgical and nonsurgical legs (n=14) at 0, 2, 4, and 8 weeks, and to evaluate bone mineral content and bone mineral density (BMD) of the proximal, mid-, and distal tibia of both the surgical and nonsurgical legs (n=15) at 0, 5, and 10 weeks.

There was significant loss of bone mineral content and lean tissue in the surgical leg compared to the nonsurgical leg.

Significant loss in bone mineral content and BMD was detected in the tibia of the surgical leg and was most pronounced in the metaphyseal region.


Source: David A. Francis, Darryl L. Millis, Laurie L. Head (2006): Bone and Lean Tissue Changes Following Cranial Cruciate Ligament Transection and Stifle Stabilization. In: Journal of the American Animal Hospital Association 42:127-135 (2006)



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SMALL ANIMAL PRACTICE

Storage temperatures and container types and the urine protein : creatinine ratios
Preanalytic protein adsorption to polymer and glass container surfaces may decrease urine protein concentration measurements and urine protein: creatinine ratios (UPC). Does urine stored in PC or glass containers have lower UPC than urine stored in HP containers? The specific objective was to determine whether clinically relevant differences in UPC would be detected after storage in glass, PC, or HP containers using common storage times and temperatures. Twelve client‐owned dogs with proteinuria helped to answer these important questions.

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