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Unusual manifestation of salmonellosis in a young foal (case report)
Diarrhea in a foal which is caused by Salmonella typhimurium is not unusual in foals. But this foal developed other clinical signs which are not obviously associated with the diarrhea, e.g. ischemic necrosis of distal limbs. A very interesting although fatal case!

A 5-month-old mixed-breed filly presented with diarrhea due to Salmonella typhimurium infection and subsequently developed pneumonia in addition to ischemic necrosis of distal limbs.

Pulmonary lesions were characterized by numerous discrete, disseminated pyogranulomas with intralesional fungal hyphae.

The morphologic characteristics of fungal hyphae were consistent with Aspergillus spp., and large numbers of A fumigatus were isolated from lung tissue via fungal culture.

Lesions in all 4 limbs were similar in distribution, duration, and severity and were characterized by coagulation necrosis accompanied by occasional thrombi in small vessels without evidence of thrombosis of larger limb arteries.

Thus, limb lesions are consistent with symmetrical peripheral gangrene, a potential complication of sepsis.



Source: M. A. Breshears, T. C. Holbrook, C. E. Haak and P. A. York (2007): Pulmonary Aspergillosis and Ischemic Distal Limb Necrosis Associated with Enteric Salmonellosis in a Foal. In: Vet Pathol 44:215-217 (2007)



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EQUINE

Silicate associated osteoporosis (SAO) in an adult horse
The horse was evaluated for a 6-month history of progressive back tenderness and acute onset of lameness. The horse had a marked (4/5) (American Association of Equine Practitioners scale) left forelimb lameness, moderate (2/5) hindlimb ataxia and weakness, and cervical pain upon palpation. Physical examination did not reveal clinical skeletal deformities or respiratory compromise. How can the diagnosis of SAO be made?

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