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Osteosarcoma in horses
In dogs osteosarcoma is a common tumor mostly affecting the legs of young to middle-aged animals of large or giant breeds. In horses, osteosarcoma is a rare tumor, with the majority of reported cases occurring in the head, and, more specifically, in the mandible of young horses. A very interesting recently published article!

The following report documents 8 cases of equine osteosarcoma, the majority occurring in male horses aged 7 years or older with a lack of metastasis identified in any horse.

Six arose in the maxilla or mandible and one in the proximal tibia.

The predominant subtype was fibroblastic osteosarcoma with fewer osteoblastic type tumors.

All had osteoid and most had a chondromucinous matrix.

Surgical excision was attempted in the majority of cases. An inability to completely excise the tumor and progressive disease typically resulted in euthanasia.

To the authors` knowledge, this case series also documents the first report of an equine extraosseous osteosarcoma within the subcutaneous tissue caudal to the shoulder. Surgical excision appears successful with no recurrence of disease 14 months later.

Further investigations of equine osteosarcoma and various chemotherapeutic agents are warranted to present additional treatment options.



Source: J. M. Bush, R. L. Fredrickson and E. J. Ehrhart (2007): Equine Osteosarcoma: A Series of 8 Cases. In: Vet Pathol 44:247-249 (2007)




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EQUINE

Limbal squamous cell carcinoma in a Rocky Mountain Horse and geneticsmembers
One privately owned Rocky Mountain Horse and 84 Rocky Mountain Horses screened for allelic frequency were enrolled in this study. The objective: To document a case of limbal squamous cell carcinoma (SCC) in a Rocky Mountain Horse stallion determined to be homozygous for the genetic risk factor (DDB2 c.1013C>T) strongly associated with the disease in Haflinger and Belgian horses, and to determine the frequency of this allele in a larger population of Rocky Mountain Horses.

  • Subconjunctival bupivacaine, lidocaine, and mepivacaine and the corneal sensitivity in horsesmembers
  • Clodronate in horses with lamenessmembers
  • Valacyclovir in horses with equine multinodular pulmonary fibrosismembers
  • Radiculopathy associated with forelimb lameness in horsesmembers
  • Biological variations of routine blood parameters in horsesmembers
  • Prognosis for horses with deep digital flexor tendon injury after penetrating woundmembers
  • Possible maternal effect for the pace trait of horsesmembers
  • Flecainide on induced atrial fibrillation in horsesmembers
  • Sonographic technique to identify manica flexoria tears in horsesmembers
  • Novel prototype dynamic laryngoplasty system on arytenoid abductionmembers
  • Lipid peroxidation biomarkers in equine neuroaxonal dystrophymembers
  • Eosinophils of the horse: an updatemembers


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