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Novel manifestation of masticatory muscle myositis
The immune-mediated disease masticatory muscle myositis is well-known in Cavalier King Charles spaniels and has a hereditary component. This very informative case report from the UK describes the same problem, a novel manifestation of this disease, in three littermates.

Clinical signs, including difficulty in opening the mouth (trismus), were seen in three of four 12-week-old cavalier King Charles spaniel littermates.

Diagnosis was established by 2M immunohistochemistry, supported by characteristic histopathological changes in affected temporal muscle.

Treatment using corticosteroids at immune-modifying doses resulted in resolution of clinical signs in all the affected animals.

Masticatory muscle myositis should be considered as a differential diagnosis in groups of young dogs with clinical signs of myositis localised to the head.




Source: Pitcher GD, Hahn CN. (2007): Atypical masticatory muscle myositis in three cavalier King Charles spaniel littermates. In: J Small Anim Pract. 2007 Apr;48(4):226-8.


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SMALL ANIMAL PRACTICE

Reference intervals for blood parameters in Shetland Sheepdogsmembers
Several breeds have physiological peculiarities that induce variations in reference intervals (RIs) compared with the general canine population. Shetland sheepdogs (SSs) are reported to be more predisposed to different diseases (eg, hyperlipidemia, gallbladder mucocele, and hypothyroidism). Consequently, a breedā€specific approach is more often required. Thus, the aim of this study was to determine whether the RIs of the general canine population could be applied to that of SSs, and to generate breedā€specific RIs, where appropriate.

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